Bon usage des antidépresseurs ISRS durant la grossesse – le défi de l'évaluation de la balance bénéfice-risque

Article Article scientifique Article Bon usage des antidépresseurs ISRS durant la grossesse – le défi de l'évaluation de la balance bénéfice-risque fre 2016 author Weisskopf Etienne 675600 author Fischer Fumeaux Céline J author Bickle Graz Myriam author Harari Mathild Morisod author Epiney Manuela 850809 Emmanuela Epiney author Borradori Tolsa Cristina 71921 author Rouiller-Cornu Sylvie 799591 author Tolsa Jean-François author Eap Chin Bin 648560 author Vial Yvan author Csajka Chantal 657943 author Panchaud-Monnat Alice 780441 561-566 27149719 1660-9379 Studies report that between 6 and 13% of women experience symptoms of depression during pregnancy and the postpartum period. The abundant data available make selective serotonin reuptake inhibitors (SSRIs) the first line treatment in pregnancy when a pharmacological treatment is required. Risks associated with the use of SSRIs during pregnancy are limited (moderate effect size) and are often not distinguishable from those inherent to the mother's disease. Yet, several questions regarding the SSRI safety profile for the unborn child are still under debate or require additional epidemiological data. The decision of SSRI use during pregnancy needs an individual evaluation of the risk-benefit balance. Antidepressive Agents/adverse effects/therapeutic use Depressive Disorder/complications/drug therapy Female Humans Practice Patterns, Physicians' Pregnancy Pregnancy Complications/chemically induced/drug therapy/psychology Risk Assessment Serotonin Uptake Inhibitors/adverse effects/therapeutic use Dewey 615 Dewey 618 31 Section des sciences pharmaceutiques 17 58 Département de pédiatrie, gynécologie et obstétrique 223 false Revue médicale suisse 12 510 6a49f692-b446-4082-916b-c97f6015c35d Article (Published version) Restricted RMS_510_561.pdf 588143 application/pdf restrictedAccess Faculté des sciences / Section des sciences pharmaceutiques Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

Title	Published in	Access level	OA Policy	Year	Views	Downloads

Bon usage des antidépresseurs ISRS durant la grossesse – le défi de l'évaluation de la balance bénéfice-risque	Revue médicale suisse			2016	695	5

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Rouiller-Cornu, Sylvie