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Title

Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants
Authors
Janaillac, Marie
Labarinas, Sonia
Pfister, Riccardo
Karam, Oliver Laurent
Published in Critical care research and practice. 2016, vol. 2016, p. 8041967
Abstract Background. In premature infants, maintaining blood partial pressure of carbon dioxide (pCO2) value within a narrow range is important to avoid cerebral lesions. The aim of this study was to assess the accuracy of a noninvasive transcutaneous method (TcpCO2), compared to blood partial pressure of carbon dioxide (pCO2). Methods. Retrospective observational study in a tertiary neonatal intensive care unit. We analyzed the correlation between blood pCO2 and transcutaneous values and the accuracy between the trends of blood pCO2 and TcpCO2 in all consecutive premature infants born at <33 weeks' gestational age. Results. 248 infants were included (median gestational age: 29 + 5 weeks and median birth weight: 1250 g), providing 1365 pairs of TcpCO2 and blood pCO2 values. Pearson's R correlation between these values was 0.58. The mean bias was -0.93 kPa with a 95% confidence limit of agreement of -4.05 to +2.16 kPa. Correlation between the trends of TcpCO2 and blood pCO2 values was good in only 39.6%. Conclusions. In premature infants, TcpCO2 was poorly correlated to blood pCO2, with a wide limit of agreement. Furthermore, concordance between trends was equally low. We warn about clinical decision-making on TcpCO2 alone when used as continuous monitoring.
Identifiers
PMID: 27375901
Full text
Article (Published version) (1.4 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département de pédiatrie
Research group Réanimation néonatale en salle d'accouchement (696)
Citation
(ISO format) 		JANAILLAC, Marie et al. Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants. In: Critical care research and practice, 2016, vol. 2016, p. 8041967. https://archive-ouverte.unige.ch/unige:96783

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Deposited on : 2017-09-15

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