Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants

Article Article scientifique Article Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants eng 2016 author Janaillac Marie 743845 author Labarinas Sonia 706945 author Pfister Riccardo 527070 author Karam Oliver Laurent 96723 8041967 10.1155/2016/8041967 27375901 2090-1305 Background. In premature infants, maintaining blood partial pressure of carbon dioxide (pCO2) value within a narrow range is important to avoid cerebral lesions. The aim of this study was to assess the accuracy of a noninvasive transcutaneous method (TcpCO2), compared to blood partial pressure of carbon dioxide (pCO2). Methods. Retrospective observational study in a tertiary neonatal intensive care unit. We analyzed the correlation between blood pCO2 and transcutaneous values and the accuracy between the trends of blood pCO2 and TcpCO2 in all consecutive premature infants born at <33 weeks' gestational age. Results. 248 infants were included (median gestational age: 29 + 5 weeks and median birth weight: 1250 g), providing 1365 pairs of TcpCO2 and blood pCO2 values. Pearson's R correlation between these values was 0.58. The mean bias was -0.93 kPa with a 95% confidence limit of agreement of -4.05 to +2.16 kPa. Correlation between the trends of TcpCO2 and blood pCO2 values was good in only 39.6%. Conclusions. In premature infants, TcpCO2 was poorly correlated to blood pCO2, with a wide limit of agreement. Furthermore, concordance between trends was equally low. We warn about clinical decision-making on TcpCO2 alone when used as continuous monitoring. Dewey 618 58 Département de pédiatrie, gynécologie et obstétrique 223 false 424 Réanimation néonatale en salle d'accouchement 696 Critical care research and practice 2016 949c6342-5198-4933-a7a6-a0b2318d9a5a Article (Published version) Restricted 8041967.pdf 1509194 application/pdf restrictedAccess Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

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Accuracy of Transcutaneous Carbon Dioxide Measurement in Premature Infants	Critical care research and practice			2016	519	0

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Janaillac, Marie