Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia
Published inBrain, behavior, and immunity, vol. 52, p. 106-119
Publication date2016
Abstract
Keywords
- Animals
- Animals, Newborn
- Brain/metabolism
- Cognition Disorders/metabolism/pathology/prevention & control
- Diffusion Magnetic Resonance Imaging
- Female
- Fingolimod Hydrochloride/therapeutic use
- Hyperoxia/drug therapy/pathology
- Lysophospholipids/metabolism
- Male
- Microglia/drug effects/metabolism/pathology
- Nerve Fibers, Myelinated/drug effects
- Oligodendroglia/drug effects/metabolism/pathology
- Oxygen/administration & dosage
- Pregnancy
- Random Allocation
- Rats
- Rats, Wistar
- Receptors, Lysosphingolipid/antagonists & inhibitors/metabolism
- Sphingosine/analogs & derivatives/metabolism
- White Matter/drug effects/metabolism/pathology
Research group
Citation (ISO format)
SERDAR, Meray et al. Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia. In: Brain, behavior, and immunity, 2016, vol. 52, p. 106–119. doi: 10.1016/j.bbi.2015.10.004
Main files (1)
Article (Published version)
Identifiers
- PID : unige:96680
- DOI : 10.1016/j.bbi.2015.10.004
- PMID : 26456693
ISSN of the journal1090-2139