Rapid detection and ruling out of neonatal sepsis by PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS)

Delco, Cristina Maria; Karam, Oliver Laurent; Pfister, Riccardo; Gervaix, Alain; Renzi, Gesuele; Emonet, Stéphane; Schrenzel, Jacques; Posfay Barbe, Klara

doi:10.1016/j.earlhumdev.2017.03.004

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Title		Rapid detection and ruling out of neonatal sepsis by PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS)
Authors		Delco, Cristina Maria Karam, Oliver Laurent Pfister, Riccardo Gervaix, Alain Renzi, Gesuele Emonet, Stéphane Schrenzel, Jacques Posfay Barbe, Klara
Published in		Early Human Development. 2017, vol. 108, p. 17-22
Abstract		Sepsis is an important cause of morbidity and mortality in neonates and clinicians are typically required to administer empiric antibiotics while waiting for blood culture results. However, prolonged and inappropriate use of antibiotics is associated with various complications and adverse events. Better tools to rapidly rule out bacterial infections are therefore needed.
Identifiers		DOI: 10.1016/j.earlhumdev.2017.03.004 PMID: 28343091
Full text		Article (Published version) (300 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique
Research groups		Analyse génomique et fonctionnelle du staphylocoque doré (604) Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183) Recherche en infectiologie pédiatrique et en pédiatrie générale (853) Réanimation néonatale en salle d'accouchement (696)
Citation (ISO format)		DELCO, Cristina Maria et al. Rapid detection and ruling out of neonatal sepsis by PCR coupled with Electrospray Ionization Mass Spectrometry (PCR/ESI-MS). In: Early Human Development, 2017, vol. 108, p. 17-22. doi: 10.1016/j.earlhumdev.2017.03.004 https://archive-ouverte.unige.ch/unige:96542