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BNP-guided therapy of chronic heart failure: what is the evidence?

Copt, Christophe
Published in Revue médicale suisse. 2009, vol. 5, no. 221, p. 2028-30, 2032-2033
Abstract The use of biomarkers, such as type B natriuretic peptide (BNP, NT pro-BNP) to finely tune the treatment during the follow-up of patients with chronic heart failure is under investigation. The few existing studies published up to now suggest that this approach leads to fewer hospital readmissions and a lower mortality due to heart failure, except in patients over 75 years of age. The positive effects of the use of biomarkers seem to be due to a greater use of target doses of the medications recommended in heart failure (angiotensin converting enzyme, angiotensin receptor blockers, or beta-blockers) and to a better adhesion to guidelines. Thus, it may prove more efficient to develop efforts to increase physicians' adhesion to guidelines than to rely on the dosage of a biomarker.
Keywords AgedChronic DiseaseFollow-Up StudiesHeart FailureHumansMiddle AgedNatriuretic Peptide, Brain
PMID: 19911688
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COPT, Christophe, NENDAZ, Mathieu. BNP-guided therapy of chronic heart failure: what is the evidence?. In: Revue médicale suisse, 2009, vol. 5, n° 221, p. 2028-30, 2032-2033. https://archive-ouverte.unige.ch/unige:9580

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Deposited on : 2010-07-12

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