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Rhodium-Catalyzed Enantioselective Isomerization of meso-Oxabenzonorbornadienes to 1,2-Naphthalene Oxides |
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Published in | Angewandte Chemie. 2017, vol. 56, no. 22, p. 6307-6311 | |
Abstract | Herein we describe a rhodium-catalyzed enantioselective isomerization of meso-oxabicyclic alkenes to 1,2-naphthalene oxides. These potentially useful building blocks can be accessed in moderate to excellent yields with impressive enantioselectivities. Additionally, experimental findings supported by preliminary computations suggest that ring-opening reactions of bridgehead disubstituted oxabicyclic alkenes proceed through the intermediacy of these epoxides and may point to a kinetically and thermodynamically favored reductive elimination as the origin for the observed enantioselectivities. | |
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Research group | Groupe Poblador Bahamonde | |
Citation (ISO format) | YEN, Andy et al. Rhodium-Catalyzed Enantioselective Isomerization of meso-Oxabenzonorbornadienes to 1,2-Naphthalene Oxides. In: Angewandte Chemie, 2017, vol. 56, n° 22, p. 6307-6311. doi: 10.1002/anie.201700632 https://archive-ouverte.unige.ch/unige:94490 |