UNIGE document Scientific Article
previous document  unige:9444  next document
add to browser collection
Title

Lymphadénopathies persistantes généralisées chez les homosexuels et les toxicomanes: altérations de l'immunité humorale et cellulaire

Authors
Aladjem, D.
Balavoine, J. F.
Chofflon, M.
Despont, J. P.
Kapanci, Y.
show hidden authors show all authors [1 - 10]
Published in Schweizerische medizinische Wochenschrift. 1986, vol. 116, no. 26, p. 873-880
Abstract In two groups of subjects at risk for acquired immune deficiency syndrome (AIDS), homosexual males and intravenous drug users with persistent generalized lymphadenopathy, humoral and cell-mediated immunity were compared. A small group of patients with definite AIDS were also studied. It was found that levels of immunoglobulins, serological markers for virus and other infections, cell-mediated immunity and histology of lymph nodes were similar in homosexuals and drug users, whereas the lymphocyte sub-populations differed completely. The number of T4+ lymphocytes was markedly decreased in homosexuals but normal in drug users; the number of T8+ lymphocytes was much higher in drug users than in homosexuals. This discrepancy may explain the extremely low prevalence of AIDS cases observed among Swiss drug users as compared with the high frequency noted among homosexuals.
Keywords Acquired Immunodeficiency Syndrome/epidemiology/ immunologyAntibody FormationHomosexualityHumansImmunity, CellularImmunoblastic Lymphadenopathy/epidemiology/ etiology/immunologyLymph Nodes/immunologyMaleOpioid-Related Disorders/epidemiology/ immunologySwitzerlandT-Lymphocytes
Identifiers
PMID: 3488588
Full text
This document has no fulltext available yet, but you can contact its author by using the form below.
Structures
Citation
(ISO format)
ROUX-LOMBARD, Pascale et al. Lymphadénopathies persistantes généralisées chez les homosexuels et les toxicomanes: altérations de l'immunité humorale et cellulaire. In: Schweizerische medizinische Wochenschrift, 1986, vol. 116, n° 26, p. 873-880. https://archive-ouverte.unige.ch/unige:9444

253 hits

0 download

Update

Deposited on : 2010-07-12

Export document
Format :
Citation style :