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Title

Cefepime plasma concentrations and clinical toxicity: a retrospective cohort study

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Published in Clinical Microbiology and Infection. 2017
Abstract Cefepime remains an important antibiotic for severe bacterial infections, yet some meta-analyses have shown elevated mortality among patients randomized to it. Therapeutic drug monitoring (TDM) of β-lactam antibiotics is increasing, but optimal plasma concentrations remain unknown. We examined clinical outcomes of patients undergoing cefepime TDM in an initial effort to define the drug's toxicity threshold.
Keywords CefepimePlasma concentrationToxicityToxicity thresholdβ-Lactam therapeutic drug monitoring
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PMID: 28111294
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Research group Thérapie cellulaire et troubles musculo-squelettiques (960)
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HUWYLER, Tibor et al. Cefepime plasma concentrations and clinical toxicity: a retrospective cohort study. In: Clinical Microbiology and Infection, 2017. https://archive-ouverte.unige.ch/unige:93761

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Deposited on : 2017-04-21

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