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Scientific article
English

Caspofungin in the treatment of oropharyngeal candidiasis

Published inInternational journal of clinical practice, vol. 57, no. 2, p. 143-144
Publication date2003
Abstract

A patient with AIDS developed oropharyngeal candidiasis. Candida albicans and C. glabrata were isolated from the patient and found to be resistant to fluconazole and itraconazole in vitro. Voriconazole therapy was initiated, but discontinued when the C. albicans strain isolated from the patient was found to be resistant to it. The patient failed to respond to subsequent therapy with a combination of amphotericin B and 5-flucytosine. Therapy with caspofungin was then initiated (70 mg loading dose, followed by 50 mg/day). The patient responded favourably to caspofungin, with complete resolution of signs and symptoms.

Keywords
  • AIDS-Related Opportunistic Infections/ drug therapy
  • Anti-Bacterial Agents/ therapeutic use
  • Antifungal Agents/ therapeutic use
  • Candidiasis/ drug therapy
  • Candidiasis, Oral/ drug therapy
  • Drug Resistance, Fungal
  • Echinocandins
  • Humans
  • Male
  • Middle Aged
  • Peptides
  • Peptides, Cyclic
  • Pharyngeal Diseases/ drug therapy
  • Treatment Outcome
Citation (ISO format)
GARBINO, Jorge et al. Caspofungin in the treatment of oropharyngeal candidiasis. In: International journal of clinical practice, 2003, vol. 57, n° 2, p. 143–144.
Identifiers
ISSN of the journal1368-5031
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