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Caspofungin in the treatment of oropharyngeal candidiasis

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Published in International Journal of Clinical Practice. 2003, vol. 57, no. 2, p. 143-144
Abstract A patient with AIDS developed oropharyngeal candidiasis. Candida albicans and C. glabrata were isolated from the patient and found to be resistant to fluconazole and itraconazole in vitro. Voriconazole therapy was initiated, but discontinued when the C. albicans strain isolated from the patient was found to be resistant to it. The patient failed to respond to subsequent therapy with a combination of amphotericin B and 5-flucytosine. Therapy with caspofungin was then initiated (70 mg loading dose, followed by 50 mg/day). The patient responded favourably to caspofungin, with complete resolution of signs and symptoms.
Keywords AIDS-Related Opportunistic Infections/ drug therapyAnti-Bacterial Agents/ therapeutic useAntifungal Agents/ therapeutic useCandidiasis/ drug therapyCandidiasis, Oral/ drug therapyDrug Resistance, FungalEchinocandinsHumansMaleMiddle AgedPeptidesPeptides, CyclicPharyngeal Diseases/ drug therapyTreatment Outcome
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PMID: 12661800
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GARBINO, Jorge et al. Caspofungin in the treatment of oropharyngeal candidiasis. In: International Journal of Clinical Practice, 2003, vol. 57, n° 2, p. 143-144. https://archive-ouverte.unige.ch/unige:9325

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Deposited on : 2010-07-12

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