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Title

Activation polyclonale B associee a l'infection par le virus d'immunodeficience humaine (VIH)

Authors
Exquis, B.
Link, L.
Scrignari, V.
Miescher, P. A.
Published in Schweizerische medizinische Wochenschrift. 1987, vol. 117, no. 47, p. 1863-1865
Abstract 87 patients with anti-HIV antibodies were divided into three groups based on the classification of the Centers for Disease Control and the following parameters reflecting polyclonal B cell activation were evaluated in these patients: immunoglobulin levels, circulating immune complexes and occurrence of autoantibodies. The results reported here indicate that intense polyclonal B cell activation occurs in both asymptomatic (CDC 2) and symptomatic patients (CDC 3 and CDC 4). Moreover, serological abnormalities were detected with similar frequency in the three groups studied.
Keywords Acquired Immunodeficiency Syndrome/ immunologyAntibodies, Viral/biosynthesisAntibody FormationAntigen-Antibody Complex/analysisAutoantibodies/biosynthesisB-Lymphocytes/ immunologyDNA/immunologyHIV/ immunologyHIV AntibodiesHIV Seropositivity/immunologyHumansImmunoglobulins/biosynthesis
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PMID: 3501163
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EXQUIS, B. et al. Activation polyclonale B associee a l'infection par le virus d'immunodeficience humaine (VIH). In: Schweizerische medizinische Wochenschrift, 1987, vol. 117, n° 47, p. 1863-1865. https://archive-ouverte.unige.ch/unige:9318

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Deposited on : 2010-07-12

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