Scientific article

Activation polyclonale B associee a l'infection par le virus d'immunodeficience humaine (VIH)

Published inSchweizerische medizinische Wochenschrift, vol. 117, no. 47, p. 1863-1865
Publication date1987

87 patients with anti-HIV antibodies were divided into three groups based on the classification of the Centers for Disease Control and the following parameters reflecting polyclonal B cell activation were evaluated in these patients: immunoglobulin levels, circulating immune complexes and occurrence of autoantibodies. The results reported here indicate that intense polyclonal B cell activation occurs in both asymptomatic (CDC 2) and symptomatic patients (CDC 3 and CDC 4). Moreover, serological abnormalities were detected with similar frequency in the three groups studied.

  • Acquired Immunodeficiency Syndrome/ immunology
  • Antibodies, Viral/biosynthesis
  • Antibody Formation
  • Antigen-Antibody Complex/analysis
  • Autoantibodies/biosynthesis
  • B-Lymphocytes/ immunology
  • DNA/immunology
  • HIV/ immunology
  • HIV Antibodies
  • HIV Seropositivity/immunology
  • Humans
  • Immunoglobulins/biosynthesis
Citation (ISO format)
EXQUIS, B. et al. Activation polyclonale B associee a l’infection par le virus d’immunodeficience humaine (VIH). In: Schweizerische medizinische Wochenschrift, 1987, vol. 117, n° 47, p. 1863–1865.
ISSN of the journal0036-7672

Technical informations

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