UNIGE document Scientific Article
previous document  unige:92895  next document
add to browser collection
Title

Alternative Strategies to Reversed-Phase Liquid Chromatography for the Analysis of Pharmaceutical Compounds

Authors
Published in American Pharmaceutical Review. 2017, vol. 20, p. 46-51
Abstract Reversed phase liquid chromatography (RPLC) is the gold standard analytical strategy in the pharmaceutical industry. In this contribution, we will describe two alternative chromatographic approaches, namely hydrophilic interaction chromatography (HILIC) and supercritical fluid chromatography (SFC), which are more and more commonly used in pharmaceutical analysis. Among their advantages, these two strategies offer better retention of polar substances, alternative selectivities and enhanced MS sensitivity, in comparison with RPLC.
Keywords Supercritical fluid chromatographyhydrophilic interaction chroma-tographySFCHILIC
Full text
Article (Published version) (1.6 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Sciences analytiques
Citation
(ISO format)
GUILLARME, Davy, VEUTHEY, Jean-Luc. Alternative Strategies to Reversed-Phase Liquid Chromatography for the Analysis of Pharmaceutical Compounds. In: American Pharmaceutical Review, 2017, vol. 20, p. 46-51. https://archive-ouverte.unige.ch/unige:92895

248 hits

1 download

Update

Deposited on : 2017-03-29

Export document
Format :
Citation style :