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Scientific article
English

Proinsulin trafckin and processing in the pancreatic B cell

Published inTrends in endocrinology and metabolism, vol. 1, no. 5, p. 261-265
Publication date1990
Abstract

Insulin is synthesized as a precursor, preproinsulin, in the rough endoplasmic reticulum of the pancreatic B cell. The combination of precursor processing and the movement of products in vesicles from one subcellular compartment to the next results in insulin becoming stored in secretory granules ready for release in response to a secretagogue.

Citation (ISO format)
HALBAN, Philippe A. Proinsulin trafckin and processing in the pancreatic B cell. In: Trends in endocrinology and metabolism, 1990, vol. 1, n° 5, p. 261–265. doi: 10.1016/1043-2760(90)90007-p
Identifiers
ISSN of the journal1043-2760
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