UNIGE document Scientific Article
previous document  unige:9150  next document
add to browser collection
Title

Internalization of 125I-insulin by IM-9 cultured human lymphocytes: a comparison between A14-monoiodo-pork and biosynthetic human insulin

Authors
Carpentier, J. L.
Renold, A. E.
Published in Diabetes Care. 1981, vol. 4, no. 2, p. 220-222
Abstract Human insulin synthesized from A- and B-chains separately produced in Escherichia coli from cloned genes was characterized by examining its interaction biochemically and morphologically with IM-9 cultured human lymphocytes. Biosynthetic human insulin (BHI) behaves similarly to pork insulin with respect both to its binding properties and to the rate and magnitude at which it is internalized by the cells.
Keywords AnimalsCell LineHumansInsulin/ analogs & derivatives/biosynthesis/metabolismIodine RadioisotopesKineticsLymphocytes/ metabolismReceptor, Insulin/ metabolismSwine
Identifiers
PMID: 7011731
Full text
Structures
Citation
(ISO format)
CARPENTIER, J. L. et al. Internalization of 125I-insulin by IM-9 cultured human lymphocytes: a comparison between A14-monoiodo-pork and biosynthetic human insulin. In: Diabetes Care, 1981, vol. 4, n° 2, p. 220-222. https://archive-ouverte.unige.ch/unige:9150

294 hits

0 download

Update

Deposited on : 2010-07-12

Export document
Format :
Citation style :