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Scientific article
English

Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production

Published inDiabetologia, vol. 59, no. 9, p. 1938-1947
Publication date2016
Abstract

Per-Arnt-Sim kinase (PASK) is a nutrient-regulated domain-containing protein kinase previously implicated in the control of insulin gene expression and glucagon secretion. Here, we explore the roles of PASK in the control of islet hormone release, by generating mice with selective deletion of the Pask gene in pancreatic beta or alpha cells.

Citation (ISO format)
SEMPLICI, Francesca et al. Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production. In: Diabetologia, 2016, vol. 59, n° 9, p. 1938–1947. doi: 10.1007/s00125-016-4025-1
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ISSN of the journal0012-186X
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