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Title

CYP17A1 Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study

Authors
Ackermann, Daniel
Escher, Geneviève
Dick, Bernhard
Al-Alwan, Heba
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Published in American Journal of Hypertension. 2016, vol. 29, no. 4, p. 484-493
Abstract Genome-wide association studies have linked CYP17A1 coding for the steroid hormone synthesizing enzyme 17α-hydroxylase (CYP17A1) to blood pressure (BP). We hypothesized that the genetic signal may translate into a correlation of ambulatory BP (ABP) with apparent CYP17A1 activity in a family-based population study and estimated the heritability of CYP17A1 activity.
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PMID: 26297028
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Structures
Research groups Traits génétiques complexes (901)
Hypertension artérielle (128)
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ACKERMANN, Daniel et al. CYP17A1 Enzyme Activity Is Linked to Ambulatory Blood Pressure in a Family-Based Population Study. In: American Journal of Hypertension, 2016, vol. 29, n° 4, p. 484-493. doi: 10.1093/ajh/hpv138 https://archive-ouverte.unige.ch/unige:90711

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Deposited on : 2016-12-21

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