Scientific article
English

The choice of the noninferiority margin in clinical trials was driven by baseline risk, type of primary outcome, and benefits of new treatment

Published in

Journal of clinical epidemiology, vol. 68, no. 10, p. 1144-1151

Publication date

2015

Abstract

To explore characteristics of clinical trials that influence the choice of the noninferiority margin (NIM) when planning the trial.

Keywords

  • Adult
  • Confidence Intervals
  • Cross-Sectional Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Models, Statistical
  • Randomized Controlled Trials as Topic
  • Research Personnel/psychology
  • Sample Size
  • Surveys and Questionnaires
  • Treatment Outcome

UNIGE research groups

Citation (ISO format)

GAYET-AGERON, Angèle et al. The choice of the noninferiority margin in clinical trials was driven by baseline risk, type of primary outcome, and benefits of new treatment. In: Journal of clinical epidemiology, 2015, vol. 68, n° 10, p. 1144–1151. doi: 10.1016/j.jclinepi.2015.01.017

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

0895-4356
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Technical informations

Creation

18/11/2016 10:09:00

First validation

18/11/2016 10:09:00

Update

15/03/2023 01:10:27

Status update

15/03/2023 01:10:26

Last indexation

14/03/2025 17:05:02
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