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Scientific article
English

Expression quantitative trait loci: present and future

Published inPhilosophical transactions - Royal Society. Biological sciences, vol. 368, no. 1620, p. 20120362-20120362
Publication date2013
Abstract

The last few years have seen the development of large efforts for the analysis of genome function, especially in the context of genome variation. One of the most prominent directions has been the extensive set of studies on expression quantitative trait loci (eQTLs), namely, the discovery of genetic variants that explain variation in gene expression levels. Such studies have offered promise not just for the characterization of functional sequence variation but also for the understanding of basic processes of gene regulation and interpretation of genome-wide association studies. In this review, we discuss some of the key directions of eQTL research and its implications.

Citation (ISO format)
NICA, Alexandra, DERMITZAKIS, Emmanouil. Expression quantitative trait loci: present and future. In: Philosophical transactions - Royal Society. Biological sciences, 2013, vol. 368, n° 1620, p. 20120362–20120362. doi: 10.1098/rstb.2012.0362
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ISSN of the journal0962-8436
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