Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation
Contributeurs/tricesTsaprouni, Loukia G; Yang, Tsun-Po; Bell, Jordana; Dick, Katherine J; Kanoni, Stavroula; Nisbet, James; Viñuela, Ana; Grundberg, Elin; Nelson, Christopher P; Meduri, Eshwar; Buil Demur, Alfonso Alberto; Cambien, Francois; Hengstenberg, Christian; Erdmann, Jeanette; Schunkert, Heribert; Goodall, Alison H; Ouwehand, Willem H; Dermitzakis, Emmanouil; Spector, Tim D; Samani, Nilesh J; Deloukas, Panos
Publié dansEpigenetics, vol. 9, no. 10, p. 1382-1396
Date de publication2014
Résumé
Mots-clés
- Adult
- Aged
- Aged, 80 and over
- CpG Islands
- DNA Methylation
- Epigenesis, Genetic
- Female
- Genome-Wide Association Study
- Humans
- Linear Models
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci
- Sequence Analysis, RNA
- Smoking/adverse effects
Structure d'affiliation
Groupe de recherche
Citation (format ISO)
TSAPROUNI, Loukia G et al. Cigarette smoking reduces DNA methylation levels at multiple genomic loci but the effect is partially reversible upon cessation. In: Epigenetics, 2014, vol. 9, n° 10, p. 1382–1396. doi: 10.4161/15592294.2014.969637
Fichiers principaux (1)
Article (Published version)
Identifiants
- PID : unige:90263
- DOI : 10.4161/15592294.2014.969637
- PMID : 25424692
ISSN du journal1559-2294