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Scientific Article
unige:9011 
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Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer |
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| Authors | ||
| Published in | Cancer Research. 2005, vol. 65, no. 8, p. 2990-2992 | |
| Abstract | The Hedgehog-GLI signaling pathway is important in animal development and tumorigenesis. Recent findings indicate that the growth and survival of human prostate cancer cells rely upon sustained signaling from the Hedgehog-GLI pathway. These findings have prompted a novel rational strategy for therapeutic treatment of prostate tumors, including metastatic tumors. | |
| Keywords | Animals — Genes, Tumor Suppressor — Hedgehog Proteins — Humans — Male — Membrane Proteins/biosynthesis/genetics/ metabolism — Oncogene Proteins/biosynthesis/genetics/ metabolism — Prostatic Neoplasms/genetics/ metabolism — Receptors, Cell Surface/biosynthesis/genetics/ metabolism — Signal Transduction — Trans-Activators/biosynthesis/genetics/ metabolism — Transcription Factors/biosynthesis/genetics/ metabolism | |
| Identifiers | PMID: 15833820 | |
| Full text |
Article - Limited access to UNIGE Other version: http://cancerres.aacrjournals.org/cgi/reprint/65/8/2990.pdf |
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| Structures | ||
| Citation (ISO format) | SANCHEZ, Pilar, CLEMENT, Virginie, RUIZ ALTABA, Ariel. Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer. In: Cancer Research, 2005, vol. 65, n° 8, p. 2990-2992. https://archive-ouverte.unige.ch/unige:9011 |
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