UNIGE document Scientific Article
previous document  unige:9011  next document
add to browser collection
Title

Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer

Authors
Sanchez, Pilar
Published in Cancer Research. 2005, vol. 65, no. 8, p. 2990-2992
Abstract The Hedgehog-GLI signaling pathway is important in animal development and tumorigenesis. Recent findings indicate that the growth and survival of human prostate cancer cells rely upon sustained signaling from the Hedgehog-GLI pathway. These findings have prompted a novel rational strategy for therapeutic treatment of prostate tumors, including metastatic tumors.
Keywords AnimalsGenes, Tumor SuppressorHedgehog ProteinsHumansMaleMembrane Proteins/biosynthesis/genetics/ metabolismOncogene Proteins/biosynthesis/genetics/ metabolismProstatic Neoplasms/genetics/ metabolismReceptors, Cell Surface/biosynthesis/genetics/ metabolismSignal TransductionTrans-Activators/biosynthesis/genetics/ metabolismTranscription Factors/biosynthesis/genetics/ metabolism
Identifiers
PMID: 15833820
Full text
Structures
Citation
(ISO format)
SANCHEZ, Pilar, CLEMENT, Virginie, RUIZ ALTABA, Ariel. Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer. In: Cancer Research, 2005, vol. 65, n° 8, p. 2990-2992. https://archive-ouverte.unige.ch/unige:9011

179 hits

0 download

Update

Deposited on : 2010-07-12

Export document
Format :
Citation style :