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| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| On the origin of metastases: Induction of pro-metastatic states after impending cell death via ER stress, reprogramming, and a cytokine storm | Cell reports | 2022 | 241 | 150 | |||
| Functional Pro-metastatic Heterogeneity Revealed by Spiked-scRNAseq Is Shaped by Cancer Cell Interactions and Restricted by VSIG1 | Cell Reports | 2020 | 311 | 137 | |||
| Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer | Biochimica et Biophysica Acta. Reviews on Cancer | 2019 | 488 | 776 | |||
| Chimeric NANOG repressors inhibit glioblastoma growth in vivo in a context-dependent manner | Scientific Reports | 2019 | 511 | 269 | |||
| The protein secretion modulator TMED9 drives CNIH4/TGFα/GLI signaling opposing TMED3-WNT-TCF to promote colon cancer metastases | Oncogene | 2019 | 368 | 227 | |||
| Long-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer Cells | PLOS ONE | 2016 | 493 | 233 | |||
| In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases | Journal of Molecular Cell Biology | 2016 | 667 | 0 | |||
| Metastases and Colon Cancer Tumor Growth Display Divergent Responses to Modulation of Canonical WNT Signaling | PloS one | 2016 | 520 | 243 | |||
| A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12 | EMBO molecular medicine | 2014 | 747 | 354 | |||
| The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer | EMBO molecular medicine | 2014 | 709 | 5 | |||
| Context-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapy | Seminars in cell & developmental biology | 2014 | 643 | 571 | |||
| On flux-limited morphogenesis | Physics of life reviews | 2013 | 603 | 3 | |||
| Morphogenetic action through flux-limited spreading | Physics of life reviews | 2013 | 711 | 5 | |||
| Hedgehog signaling and the Gli code in stem cells, cancer, and metastases | Science signaling | 2011 | 790 | 8 | |||
| Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas | EMBO molecular medicine | 2010 | 637 | 0 | |||
| Hedgehog pathway activity is required for the lethality and intestinal phenotypes of mice with hyperactive Wnt signaling | Mechanisms of development | 2010 | 657 | 0 | |||
| NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53 | EMBO journal | 2010 | 686 | 0 | |||
| BMP signaling promotes the growth of primary human colon carcinomas in vivo | Journal of Molecular Cell Biology | 2010 | 641 | 0 | |||
| Small molecule modulation of HH-GLI signaling: current leads, trials and tribulations | Biochemical pharmacology | 2010 | 532 | 0 | |||
| Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals | Journal of Molecular Cell Biology | 2010 | 598 | 0 | |||
| Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion | EMBO molecular medicine | 2009 | 645 | 0 | |||
| Entity versus property: tracking the nature, genesis and role of stem cells in cancer. Conference on Stem cells and cancer | EMBO reports | 2009 | 560 | 0 | |||
| A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers | EMBO journal | 2009 | 607 | 0 | |||
| Therapeutic inhibition of Hedgehog-GLI signaling in cancer: epithelial, stromal, or stem cell targets? | Cancer cell | 2008 | 624 | 2 | |||
| Regulation of survival in adult hippocampal and glioblastoma stem cell lineages by the homeodomain-only protein HOP | Neural development | 2008 | 652 | 363 | |||
| The Gli code: an information nexus regulating cell fate, stemness and cancer | Trends in cell biology | 2007 | 858 | 351 | |||
| HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity | Current biology | 2007 | 668 | 685 | |||
| Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 542 | 0 | |||
| In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice | Mechanisms of development | 2005 | 595 | 0 | |||
| Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer | Cancer research | 2005 | 601 | 0 | |||
| Interference with HH-GLI signaling inhibits prostate cancer | Trends in molecular medicine | 2005 | 626 | 0 | |||
| Brain as a paradigm of organ growth: Hedgehog-Gli signaling in neural stem cells and brain tumors | Journal of neurobiology | 2005 | 599 | 0 | |||
| Cooperative requirement of the Gli proteins in neurogenesis | Development | 2005 | 585 | 461 | |||
| Sonic hedgehog controls stem cell behavior in the postnatal and adult brain | Development | 2005 | 764 | 372 | |||
| Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 660 | 0 | |||
| Hedgehog--Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer | Cancer Letters | 2004 | 163 | 0 | |||
| Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex | Development | 2004 | 598 | 0 | |||
| Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features | Proceedings of the National Academy of Sciences | 2003 | 181 | 0 | |||
| Development. Longing for ligand: hedgehog, patched, and cell death | Science | 2003 | 167 | 0 | |||
| The emergent design of the neural tube: prepattern, SHH morphogen and GLI code | Current Opinion in Genetics & Development | 2003 | 153 | 0 | |||
| Gli and hedgehog in cancer: tumours, embryos and stem cells | Nature Reviews Cancer | 2002 | 165 | 0 | |||
| Hedgehog-Gli signalling and the growth of the brain | Nature Reviews Neuroscience | 2002 | 164 | 0 | |||
| Pathways and consequences: Hedgehog signaling in human disease | Trends in Cell Biology | 2002 | 192 | 0 | |||
| A gene expression map of human chromosome 21 orthologues in the mouse | Nature | 2002 | 169 | 0 | |||
| Growth, hedgehog and the price of GAS | BioEssays | 2002 | 129 | 0 | |||
| Embryonic regionalization of the neocortex | Mechanisms of Development | 2001 | 159 | 171 | |||
| Wnt signals are targets and mediators of Gli function | Current Biology | 2001 | 165 | 121 | |||
| Hexokinase I is a Gli2-responsive gene expressed in the embryonic CNS | Mechanisms of Development | 2000 | 145 | 133 | |||
| Gli proteins and Hedgehog signaling: development and cancer | Trends in Genetics | 1999 | 152 | 0 | |||
| The works of GLI and the power of hedgehog | Nature Cell Biology | 1999 | 122 | 0 | |||
| Carboxy-terminally truncated Gli3 proteins associate with Smads | Nature Genetics | 1998 | 157 | 0 | |||
| Gli/Zic factors pattern the neural plate by defining domains of cell differentiation | Nature | 1998 | 179 | 0 | |||
| Cooperation of intrinsic and extrinsic signals in the elaboration of regional identity in the posterior cerebral cortex | Current Biology | 1998 | 162 | 96 | |||
| Neural patterning. Deconstructing the organizer | Nature | 1998 | 149 | 0 | |||
| Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours | Nature | 1997 | 170 | 0 | |||
| Catching a Gli-mpse of Hedgehog | Cell | 1997 | 148 | 76 | |||
| Coexpression of HNF-3 beta and Isl-1/2 and mixed distribution of ventral cell types in the early neural tube | International Journal of Developmental Biology | 1996 | 140 | 0 | |||
| Involvement of Livertine, a hepatocyte growth factor family member, in neural morphogenesis | Mechanisms of Development | 1996 | 170 | 120 | |||
| Restrictions to floor plate induction by hedgehog and winged-helix genes in the neural tube of frog embryos | Molecular and Cellular Neuroscience | 1995 | 177 | 0 | |||
| Early stages of notochord and floor plate development in the chick embryo defined by normal and induced expression of HNF-3 beta | Developmental Biology | 1995 | 196 | 204 | |||
| Pattern formation in the vertebrate neural plate | Trends in Neurosciences | 1994 | 141 | 0 | |||
| Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord | Cell | 1994 | 151 | 0 | |||
| The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo | Cell | 1994 | 197 | 0 | |||
| Midline cells and the organization of the vertebrate neuraxis | Current Opinion in Genetics & Development | 1993 | 141 | 0 | |||
| Sequential expression of HNF-3 beta and HNF-3 alpha by embryonic organizing centers: the dorsal lip/node, notochord and floor plate | Mechanisms of Development | 1993 | 180 | 0 | |||
| Ectopic neural expression of a floor plate marker in frog embryos injected with the midline transcription factor Pintallavis | Proceedings of the National Academy of Sciences | 1993 | 153 | 0 | |||
| Vertebrate development: an emerging synthesis | Trends in Genetics | 1991 | 128 | 0 | |||
| Retinoic acid modifies mesodermal patterning in early Xenopus embryos | Genes and Development | 1991 | 193 | 134 | |||
| Axial patterning and the establishment of polarity in the frog embryo | Trends in Genetics | 1990 | 164 | 0 | |||
| Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis | Cell | 1989 | 166 | 0 | |||
| Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos | Nature | 1989 | 159 | 0 | |||
| Organization and expression of the Plasmodium knowlesi circumsporozoite antigen gene | Molecular and Biochemical Parasitology | 1987 | 160 | 0 | |||
| Xfin: an embryonic gene encoding a multifingered protein in Xenopus | EMBO Journal | 1987 | 170 | 0 | |||
| Expression of the Plasmodium knowlesi circumsporozoite antigen in Escherichia coli directed by Plasmodium bacterial-like promoter sequences | Gene | 1986 | 147 | 0 | |||
| Promotion, termination, and anti-termination in the rpsU-dnaG-rpoD macromolecular synthesis operon of E. coli K-12 | Molecular and General Genetics | 1984 | 185 | 0 |
