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Title

Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors

Authors
Musset, Thierry
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Published in Archives of Internal Medicine. 2006, vol. 166, no. 12, p. 1280-1287
Abstract Drug-induced long QT syndrome is a serious adverse drug reaction. Methadone prolongs the QT interval in vitro in a dose-dependent manner. In the inpatient setting, the frequency of QT interval prolongation with methadone treatment, its dose dependence, and the importance of cofactors such as drug-drug interactions remain unknown.
Keywords AdolescentAdultElectrocardiographyFemaleFollow-Up StudiesHumansLong QT Syndrome/chemically induced/epidemiology/physiopathologyMaleMethadone/adverse effectsMiddle AgedNarcotics/adverse effectsPrevalenceRetrospective StudiesRisk FactorsSubstance Abuse, Intravenous/rehabilitation
Identifiers
PMID: 16801510
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Article (Published version) (239 Kb) - public document Free access
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Research group Groupe Desmeules Jules (pharmacologie/toxicologie) (567)
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EHRET, Georg Benedikt et al. Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors. In: Archives of Internal Medicine, 2006, vol. 166, n° 12, p. 1280-1287. https://archive-ouverte.unige.ch/unige:90104

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Deposited on : 2016-12-08

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