Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors

Article Article scientifique Article Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors eng 2006 author Ehret Georg Benedikt 98462 author Voide Cathy 630105 author Gex-Fabry Marianne 592985 author Chabert Jocelyne 628070 author Shah Dipen 559124 author Broers Barbara 28005 author Piguet Valérie 64458 author Musset Thierry author Gaspoz Jean-Michel 126367 author Perrier Arnaud 27944 author Dayer Pierre 25460 author Desmeules Jules Alexandre 73542 1280-1287 10.1001/archinte.166.12.1280 16801510 0003-9926 Drug-induced long QT syndrome is a serious adverse drug reaction. Methadone prolongs the QT interval in vitro in a dose-dependent manner. In the inpatient setting, the frequency of QT interval prolongation with methadone treatment, its dose dependence, and the importance of cofactors such as drug-drug interactions remain unknown. Adolescent Adult Electrocardiography Female Follow-Up Studies Humans Long QT Syndrome/chemically induced/epidemiology/physiopathology Male Methadone/adverse effects Middle Aged Narcotics/adverse effects Prevalence Retrospective Studies Risk Factors Substance Abuse, Intravenous/rehabilitation Dewey 613 Dewey 616 Dewey 616.89 Dewey 617 56 Département de médecine 221 60 Département de psychiatrie 225 63 Département d'anesthésiologie, pharmacologie, soins intensifs et urgences 229 64 Département de santé et médecine communautaires 22A false 302 Groupe Desmeules Jules (pharmacologie/toxicologie) 567 Archives of internal medicine 166 12 1efc0c48-fec0-416e-9b9d-96a9ef337699 Article (Published version) Public ioi60031.pdf 244270 application/pdf openAccess Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département de psychiatrie Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires

Title	Published in	Year	Views	Downloads

Drug-induced long QT syndrome in injection drug users receiving methadone: high frequency in hospitalized patients and risk factors	Archives of internal medicine	2006	489	420
SIADH consecutive to ciprofloxacin intake	European journal of internal medicine	2004	488	2

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