NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro
Published inDiabetologia, vol. 44, no. 10, p. 1281-1295
Publication date2001
Abstract
Keywords
- Animals
- Antibodies, Monoclonal/pharmacology
- Apoptosis
- Carrier Proteins/metabolism
- Cell Line
- Cells, Cultured
- Coculture Techniques
- DNA Fragmentation
- Enzyme Activation
- Flow Cytometry
- Fluorescent Antibody Technique
- Gene Expression
- Humans
- Islets of Langerhans/ cytology/ metabolism
- JNK Mitogen-Activated Protein Kinases
- MAP Kinase Kinase 4
- Male
- Mice
- Mice, Transgenic
- Middle Aged
- Mitogen-Activated Protein Kinase Kinases/metabolism
- Nerve Growth Factor/genetics/immunology/ physiology
- Nucleosomes/ultrastructure
- PC12 Cells
- Phosphatidylserines/metabolism
- Phosphorylation
- Protein-Serine-Threonine Kinases
- Proto-Oncogene Proteins/metabolism
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-bcl-2/metabolism
- RNA, Messenger/analysis
- Rats
- Receptor, Nerve Growth Factor
- Receptor, trkA/analysis/genetics
- Receptors, Nerve Growth Factor/analysis/genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction
- Bcl-Associated Death Protein
- Bcl-X Protein
Affiliation
Citation (ISO format)
PIERUCCI, D. et al. NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro. In: Diabetologia, 2001, vol. 44, n° 10, p. 1281–1295.
Main files (1)
Article
Identifiers
- PID : unige:8966
- PMID : 11692177
ISSN of the journal0012-186X