Fast and efficient QTL mapper for thousands of molecular phenotypes

Ongen, Halit; Buil Demur, Alfonso Alberto; Brown, Andrew Anand; Dermitzakis, Emmanouil; Delaneau, Olivier

doi:10.1093/bioinformatics/btv722

Scientific article

English

Fast and efficient QTL mapper for thousands of molecular phenotypes

ContributorsOngen, Halit; Buil Demur, Alfonso Alberto; Brown, Andrew Anand; Dermitzakis, Emmanouil; Delaneau, Olivier

Published inBioinformatics, vol. 32, no. 10, p. 1479-1485

Publication date2016

Abstract

In order to discover quantitative trait loci, multi-dimensional genomic datasets combining DNA-seq and ChiP-/RNA-seq require methods that rapidly correlate tens of thousands of molecular phenotypes with millions of genetic variants while appropriately controlling for multiple testing.

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de médecine génétique et développement

Research groups

Population Genomics and Genetics of Complex Traits (892)

Citation (ISO format)

ONGEN, Halit et al. Fast and efficient QTL mapper for thousands of molecular phenotypes. In: Bioinformatics, 2016, vol. 32, n° 10, p. 1479–1485. doi: 10.1093/bioinformatics/btv722

Article (Published version)

Identifiers

PID : unige:89649
DOI : 10.1093/bioinformatics/btv722
PMID : 26708335

Journal ISSN1367-4803

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Creation23/11/2016 15:37:00

First validation23/11/2016 15:37:00

Update15/03/2023 01:02:25

Status update15/03/2023 01:02:24

Last indexation31/10/2024 05:18:58

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Fast and efficient QTL mapper for thousands of molecular phenotypes

In order to discover quantitative trait loci, multi-dimensional genomic datasets combining DNA-seq and ChiP-/RNA-seq require methods that rapidly correlate tens of thousands of molecular phenotypes with millions of genetic variants while appropriately controlling for multiple testing.

Technical informations