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Scientific Article
unige:89553 
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Effect of estetrol on Beta-Endorphin level in female rats |
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| Authors | ||
| Published in | Steroids. 2015, vol. 95, p. 104-110 | |
| Abstract | Estetrol (E4), a naturally occurring estrogen produced exclusively by human fetal liver, is currently being evaluated for potential use in contraception and menopausal care in humans. The present study was designed to profile E4 effects on the central nervous system, to assess the in vivo effects of E4 administration on Beta-Endorphin (β-END) release in specific brain structures and to evaluate whether E4 has synergic or antagonistic effects on estradiol-mediated β-END synthesis. | |
| Keywords | Animals — Dose-Response Relationship, Drug — Drug Antagonism — Drug Synergism — Estetrol/pharmacology — Estradiol/analogs & derivatives/pharmacology — Female — Ovariectomy — Rats — Rats, Wistar — beta-Endorphin/metabolism | |
| Identifiers | PMID: 25595451 | |
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| Structures | ||
| Research group | Groupe Petignat Patrick (933) | |
| Citation (ISO format) | PLUCHINO, Nicola et al. Effect of estetrol on Beta-Endorphin level in female rats. In: Steroids, 2015, vol. 95, p. 104-110. https://archive-ouverte.unige.ch/unige:89553 |
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