UNIGE document Scientific Article
previous document  unige:8938  next document
add to browser collection
Title

Complementary pathways in mammalian female sex determination

Authors
Published in Journal of Biology. 2009, vol. 8, no. 8, p. 74
Abstract In mammals, the sex of the embryo is determined by the fate of the gonad. Recent papers, including one in BMC Developmental Biology, shed light on the molecular regulation of ovarian development and suggest that the R-spondin1/Wnt4/beta-catenin pathway and the Foxl2 transcription factor act in a complementary manner to promote ovarian fate and to repress testicular development.
Keywords AnimalsEmbryo, Mammalian/embryology/physiologyFemaleForkhead Transcription Factors/metabolismGene Expression Regulation, DevelopmentalHumansMaleOvary/ embryology/physiologySex Determination (Genetics)Signal TransductionThrombospondins/metabolismWnt Proteins/metabolismBeta Catenin/metabolism
Identifiers
PMID: 19735582
Full text
Structures
Citation
(ISO format)
NEF, Serge, VASSALLI, Jean-Dominique. Complementary pathways in mammalian female sex determination. In: Journal of Biology, 2009, vol. 8, n° 8, p. 74. https://archive-ouverte.unige.ch/unige:8938

198 hits

0 download

Update

Deposited on : 2010-07-12

Export document
Format :
Citation style :