SN
Nef, Serge
Affiliation entities
Research groups
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse | 2024 | 46 | 18 | ||||
Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse | eLife | 2024 | 16 | 10 | |||
In vitro differentiation of mouse pluripotent stem cells into corticosteroid-producing adrenocortical cells | Stem cell reports | 2024 | 12 | 2 | |||
Association between self-reported mobile phone use and the semen quality of young men | Fertility and sterility | 2023 | 11 | 2 | |||
Single-cell transcriptomic profiling redefines the origin and specification of early adrenogonadal progenitors | Cell reports | 2023 | 40 | 88 | |||
Mutations in STARD8 (DLC3) May Cause 46,XY Gonadal Dysgenesis | Sexual development | 2023 | 11 | 0 | |||
Low-polarity untargeted metabolomic profiling as a tool to gain insight into seminal fluid | Metabolomics | 2023 | 45 | 47 | |||
The −KTS splice variant of WT1 is essential for ovarian determination in mice | Science | 2023 | 14 | 4 | |||
Gonadotropin axis and semen quality in young swiss men after cannabis consumption: effect of chronicity and modulation by cannabidiol | Andrology | 2023 | 61 | 0 | |||
The action of physiological and synthetic steroids on the calcium channel CatSper in human sperm | Frontiers in cell and developmental biology | 2023 | 48 | 14 | |||
The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation | PLOS genetics | 2023 | 36 | 11 | |||
Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis | Development | 2023 | 14 | 2 | |||
Oligogenic heterozygous inheritance of sperm abnormalities in mouse | eLife | 2022 | 128 | 137 | |||
Loss of NEDD4 causes complete XY gonadal sex reversal in mice | Cell death and disease | 2022 | 128 | 49 | |||
Deciphering the origins and fates of steroidogenic lineages in the mouse testis | Cell reports | 2022 | 167 | 99 | |||
A conserved function of Human DLC3 and Drosophila Cv-c in testis development | eLife | 2022 | 60 | 25 | |||
Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad | Science advances | 2022 | 160 | 58 | |||
TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway | Nature communications | 2022 | 158 | 108 | |||
Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors | Nature communications | 2022 | 119 | 87 | |||
Specific transcriptomic signatures and dual regulation of steroidogenesis between fetal and adult mouse leydig cells | Frontiers in Cell and Developmental Biology | 2021 | 150 | 127 | |||
Combined Use of Whole Exome Sequencing and CRISPR/Cas9 to Study the Etiology of Non-Obstructive Azoospermia: Demonstration of the Dispensable Role of the Testis-Specific Genes C1orf185 and CCT6B | Cells | 2021 | 118 | 55 | |||
Maternal occupational exposure to endocrine-disrupting chemicals during pregnancy and semen parameters in adulthood: results of a nationwide cross-sectional study among Swiss conscripts | Human Reproduction | 2021 | 156 | 1 | |||
A Novel WT1 Mutation Identified in a 46,XX Testicular/Ovotesticular DSD Patient Results in the Retention of Intron 9 | Biology | 2021 | 275 | 100 | |||
Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination | FASEB Journal | 2021 | 147 | 101 | |||
The antidepressant Sertraline inhibits CatSper Ca2+ channels in human sperm | Human reproduction | 2021 | 179 | 127 | |||
Pantoprazole, a proton-pump inhibitor, impairs human sperm motility and capacitation in vitro | Andrology | 2020 | 231 | 0 | |||
Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary | Science Advances | 2020 | 231 | 117 | |||
Steroid profile analysis by LC-HRMS in human seminal fluid | Journal of Chromatography. B | 2020 | 332 | 78 | |||
Semen endocannabinoids are correlated to sperm quality in a cohort of 200 young Swiss men | Andrology | 2020 | 286 | 2 | |||
Protection against XY gonadal sex reversal by a variant region on mouse chromosome 13 | Genetics | 2020 | 223 | 125 | |||
Genetic ablation of MiR-22 fosters diet-induced obesity and NAFLD development | Journal of Personalized Medicine | 2020 | 250 | 145 | |||
Deficiency in insulin-like growth factors signalling in mouse Leydig cells increase conversion of testosterone to estradiol because of feminization | Acta Physiologica | 2020 | 152 | 0 | |||
Meiosis occurs normally in the fetal ovary of mice lacking all retinoic acid receptors | Science Advances | 2020 | 249 | 136 | |||
The gene encoding the ketogenic enzyme HMGCS2 displays a unique expression during gonad development in mice | PLOS ONE | 2020 | 267 | 148 | |||
CatSper: The complex main gate of calcium entry in mammalian spermatozoa | Molecular and Cellular Endocrinology | 2020 | 201 | 234 | |||
Regional difference in semen quality of young men: a review on the implication of environmental and lifestyle factors during fetal life and adulthood | Basic and Clinical Andrology | 2020 | 210 | 158 | |||
Ablation of the canonical testosterone production pathway via knockout of the steroidogenic enzyme HSD17B3, reveals a novel mechanism of testicular testosterone production | FASEB Journal | 2020 | 155 | 98 | |||
The insulin/IGF system in mammalian sexual development and reproduction | International Journal of Molecular Sciences | 2019 | 266 | 137 | |||
Genetic resistance to DEHP-induced transgenerational endocrine disruption | PLOS ONE | 2019 | 451 | 286 | |||
Genetic Control of Gonadal Sex Determination and Development | Trends in Genetics | 2019 | 474 | 532 | |||
Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome | Genetics in Medicine | 2019 | 353 | 190 | |||
Semen quality of young men in Switzerland: a nationwide cross‐sectional population‐based study | Andrology | 2019 | 686 | 247 | |||
The ReproGenomics Viewer: a multi-omics and cross-species resource compatible with single-cell studies for the reproductive science community | Bioinformatics | 2019 | 351 | 0 | |||
Dissecting Cell Lineage Specification and Sex Fate Determination in Gonadal Somatic Cells Using Single-Cell Transcriptomics | Cell Reports | 2019 | 399 | 220 | |||
Tumor Suppressor PTEN Regulates Negatively Sertoli Cell Proliferation, Testis Size, and Sperm Production In Vivo | Endocrinology | 2019 | 415 | 97 | |||
Bi-allelic Mutations in ARMC2 Lead to Severe Astheno-Teratozoospermia Due to Sperm Flagellum Malformations in Humans and Mice | American Journal of Human Genetics | 2019 | 373 | 0 | |||
Characterizing the bipotential mammalian gonad | Current Topics in Developmental Biology | 2019 | 387 | 450 | |||
Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss men | Clinical Biochemistry | 2018 | 483 | 3 | |||
Creation of knock out and knock in mice by CRISPR/Cas9 to validate candidate genes for human male infertility, interest, difficulties and feasibility | Molecular and Cellular Endocrinology | 2018 | 406 | 1 | |||
Insulin/IGF1 signalling regulates the mitochondrial biogenesis markers in steroidogenic cells of prepubertal testis, but not ovary | Biology of Reproduction | 2018 | 361 | 0 | |||
The impact of new technologies in our understanding of testis formation and function | Molecular and Cellular Endocrinology | 2018 | 353 | 325 | |||
A brief history of sex determination | Molecular and Cellular Endocrinology | 2018 | 328 | 3 | |||
Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells | FASEB Journal | 2018 | 345 | 1 | |||
Single cell transcriptome sequencing: A new approach for the study of mammalian sex determination | Molecular and Cellular Endocrinology | 2018 | 376 | 0 | |||
A Case of Two Sisters Suffering from 46,XY Gonadal Dysgenesis and Carrying a Mutation of a Novel Candidate Sex-Determining Gene STARD8 on the X Chromosome | Sexual Development | 2018 | 375 | 328 | |||
NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis | Molecular and Cellular Endocrinology | 2018 | 366 | 492 | |||
Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA Sequencing | Cell Reports | 2018 | 395 | 184 | |||
ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling | Proceedings of the National Academy of Sciences | 2018 | 362 | 150 | |||
Mutations in CFAP43 and CFAP44 cause male infertility and flagellum defects in Trypanosoma and human | Nature Communications | 2018 | 415 | 341 | |||
PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice | EMBO Molecular Medicine | 2018 | 429 | 0 | |||
Sertoli Cell Number Defines and Predicts Germ and Leydig Cell Population Sizes in the Adult Mouse Testis | Endocrinology | 2017 | 456 | 1 | |||
Testicular Dysgenesis Syndrome and Long-Lasting Epigenetic Silencing of Mouse Sperm Genes Involved in the Reproductive System after Prenatal Exposure to DEHP | PloS one | 2017 | 615 | 277 | |||
SPINK2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes | EMBO Molecular Medicine | 2017 | 422 | 0 | |||
Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex | Science | 2016 | 889 | 0 | |||
MPC1-like Is a Placental Mammal-specific Mitochondrial Pyruvate Carrier Subunit Expressed in Postmeiotic Male Germ Cells | The Journal of biological chemistry | 2016 | 543 | 229 | |||
Stress-activated miR-21/miR-21* in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption | Gut | 2016 | 678 | 0 | |||
Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP | Human molecular genetics | 2016 | 497 | 0 | |||
DICER Regulates the Formation and Maintenance of Cell-Cell Junctions in the Mouse Seminiferous Epithelium | Biology of reproduction | 2015 | 452 | 0 | |||
A Case of Wiedemann-Steiner Syndrome Associated with a 46,XY Disorder of Sexual Development and Gonadal Dysgenesis | Sexual development | 2015 | 642 | 0 | |||
Research resource: the dynamic transcriptional profile of sertoli cells during the progression of spermatogenesis | Molecular endocrinology | 2015 | 471 | 1 | |||
Autocrine Action of IGF2 Regulates Adult β-Cell Mass and Function | Diabetes | 2015 | 555 | 0 | |||
Loss of Function Mutation in the Palmitoyl-Transferase HHAT Leads to Syndromic 46,XY Disorder of Sex Development by Impeding Hedgehog Protein Palmitoylation and Signaling | PLOS genetics | 2014 | 648 | 272 | |||
The emerging role of insulin-like growth factors in testis development and function | Basic and clinical andrology | 2014 | 453 | 185 | |||
Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis | Development | 2014 | 661 | 438 | |||
Germ cell-specific targeting of DICER or DGCR8 reveals a novel role for endo-siRNAs in the progression of mammalian spermatogenesis and male fertility | PloS one | 2014 | 428 | 205 | |||
An Essential Role for Insulin and IGF1 Receptors in Regulating Sertoli Cell Proliferation, Testis Size, and FSH Action in Mice | Molecular endocrinology | 2013 | 639 | 668 | |||
Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice | PLOS genetics | 2013 | 691 | 343 | |||
Cellular source and mechanisms of high transcriptome complexity in the mammalian testis | Cell reports | 2013 | 719 | 663 | |||
DNA Methylation Profiling of the Fibrinogen Gene Landscape in Human Cells and during Mouse and Zebrafish Development | PloS one | 2013 | 617 | 304 | |||
Petits ARN non condants et spermatogenèse | MS. Médecine sciences | 2012 | 568 | 490 | |||
The Glucocorticoid-induced leucine zipper (GILZ) Is essential for spermatogonial survival and spermatogenesis | Sexual development | 2012 | 591 | 394 | |||
Prevention of Diabetes in db/db Mice by Dietary Soy Is Independent of Isoflavone Levels | Endocrinology | 2012 | 573 | 0 | |||
Soy, phytoestrogens and their impact on reproductive health | Molecular and cellular endocrinology | 2012 | 977 | 3 216 | |||
Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice | PloS one | 2012 | 543 | 280 | |||
Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes | Biology of reproduction | 2011 | 627 | 1 080 | |||
Hematopoietic prostaglandin D synthase (H-Pgds) is expressed in the early embryonic gonad and participates to the initial nuclear translocation of the SOX9 protein | Developmental dynamics | 2011 | 570 | 0 | |||
Dicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defects | PloS one | 2011 | 631 | 289 | |||
Dicer is required for haploid male germ cell differentiation in mice | PloS one | 2011 | 500 | 298 | |||
Loss of Dicer in Sertoli cells has a major impact on the testicular proteome of mice | Molecular & cellular proteomics | 2011 | 666 | 0 | |||
The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis | Human molecular genetics | 2011 | 673 | 0 | |||
FSH-stimulated PTEN activity accounts for the lack of FSH mitogenic effect in prepubertal rat Sertoli cells | Molecular and cellular endocrinology | 2010 | 495 | 0 | |||
Loss of Insl3: a potential predisposing factor for testicular torsion | The Journal of urology | 2010 | 551 | 0 | |||
Potential detrimental effects of a phytoestrogen-rich diet on male fertility in mice | Molecular and cellular endocrinology | 2010 | 641 | 0 | |||
Soy, phyto-oestrogens and male reproductive function: a review | International journal of andrology | 2010 | 542 | 12 | |||
microRNAs in the testis: building up male fertility | Journal of andrology | 2010 | 421 | 0 | |||
Reply by authors | The Journal of urology | 2010 | 488 | 0 | |||
The molecular chaperone Hsp90alpha is required for meiotic progression of spermatocytes beyond pachytene in the mouse | PloS one | 2010 | 644 | 360 | |||
Sertoli cell Dicer is essential for spermatogenesis in mice | Developmental biology | 2009 | 638 | 0 | |||
Insulin receptor and IGF1R are not required for oocyte growth, differentiation, and maturation in mice | Sexual development | 2009 | 554 | 0 | |||
Dcp1-bodies in mouse oocytes | Molecular biology of the cell | 2009 | 491 | 0 | |||
Complementary pathways in mammalian female sex determination | Journal of biology | 2009 | 595 | 136 | |||
Fetal programming of adult glucose homeostasis in mice | PloS one | 2009 | 603 | 440 | |||
Perinatal exposure to bisphenol a alters early adipogenesis in the rat | Environmental health perspectives | 2009 | 548 | 0 | |||
Special issue on the topic: Role of endocrine disruptors from the environment in the aetiology of obesity and diabetes | Molecular and cellular endocrinology | 2009 | 600 | 0 | |||
Soy, phytoestrogens and metabolism: A review | Molecular and cellular endocrinology | 2009 | 474 | 0 | |||
Pancreatic insulin content regulation by the estrogen receptor ER alpha | PloS one | 2008 | 727 | 512 | |||
Diethystilbestrol action on Leydig cell function and testicular descent | Chimia | 2008 | 559 | 0 | |||
Dietary phytoestrogens activate AMP-activated protein kinase with improvement in lipid and glucose metabolism | Diabetes | 2008 | 652 | 1 | |||
Genetic programs that regulate testicular and ovarian development | Molecular and cellular endocrinology | 2007 | 526 | 0 | |||
De l'épigénétique et du développement | Revue médicale suisse | 2007 | 537 | 0 | |||
A phytoestrogen-rich diet increases energy expenditure and decreases adiposity in mice | Environmental health perspectives | 2007 | 638 | 0 | |||
Estrogen receptor alpha is a major contributor to estrogen-mediated fetal testis dysgenesis and cryptorchidism | Endocrinology | 2007 | 606 | 306 | |||
Expression of serpinb6 serpins in germ and somatic cells of mouse gonads | Molecular reproduction and development | 2006 | 491 | 0 | |||
Prostaglandin D2 induces nuclear import of the sex-determining factor SOX9 via its cAMP-PKA phosphorylation | EMBO journal | 2005 | 532 | 0 | |||
Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development | Developmental biology | 2005 | 587 | 1 | |||
Induction of enhanced green fluorescent protein expression in response to lesions in the nervous system | Journal of comparative neurology | 2004 | 593 | 0 | |||
Emotions are building up in the field of extracellular proteolysis | Trends in molecular medicine | 2003 | 505 | 0 | |||
In vivo role of truncated trkb receptors during sensory ganglion neurogenesis | Neuroscience | 2003 | 472 | 0 | |||
Testis determination requires insulin receptor family function in mice | Nature | 2003 | 571 | 0 | |||
cpp32 messenger RNA neosynthesis is induced by fatal axotomy and is not regulated by athanatal Bcl-2 over-expression | Neuroscience | 1999 | 25 | 0 | |||
Regulation of rhodopsin phosphorylation by a family of neuronal calcium sensors | Biochemical and biophysical research communications | 1995 | 532 | 1 | |||
Identification of a neuronal calcium sensor (NCS-1) possibly involved in the regulation of receptor phosphorylation | Journal of receptor and signal transduction research | 1995 | 80 | 0 | |||
Cation binding and conformational changes in VILIP and NCS-1, two neuron-specific calcium-binding proteins | The Journal of biological chemistry | 1994 | 507 | 0 |