Pancreatic-specific inactivation of IGF-I gene causes enlarged pancreatic islets and significant resistance to diabetes
ContributorsLu, Yarong; Herrera, Pedro Luis; Guo, Yubin; Sun, David; Tang, Zhengyi; LeRoith, Derek; Liu, J. L.
Published inDiabetes, vol. 53, no. 12, p. 3131-3141
Publication date2004
Abstract
Keywords
- Animals
- Apoptosis
- Blood Glucose/metabolism
- Female
- Gene Silencing/ physiology
- Glucagon/blood
- Glucose Tolerance Test
- Immunity, Innate/genetics
- Insulin/blood
- Insulin-Like Growth Factor I/ deficiency/ genetics
- Islets of Langerhans/ cytology
- Male
- Mice
- Mice, Inbred DBA
- Mice, Knockout
- Pancreas/ physiology
Affiliation
Research group
Citation (ISO format)
LU, Yarong et al. Pancreatic-specific inactivation of IGF-I gene causes enlarged pancreatic islets and significant resistance to diabetes. In: Diabetes, 2004, vol. 53, n° 12, p. 3131–3141. doi: 10.2337/diabetes.53.12.3131
Main files (1)
Article
Identifiers
- PID : unige:8867
- DOI : 10.2337/diabetes.53.12.3131
- PMID : 15561943
ISSN of the journal0012-1797