UNIGE document Scientific Article
previous document  unige:8488  next document
add to browser collection
Title

Creation of Quaternary Stereogenic Centers via Copper-Catalyzed Asymmetric Conjugate Addition of Alkenyl Alanes to α,β-Unsaturated Cyclic Ketones

Authors
Müller, Daniel
Published in Synlett. 2010, vol. 2010, no. 11, p. 1694 - 1698
Abstract SimplePhos ligands proved to be very powerful ligands in the generation of quaternary stereogenic centers by Michael addition of alkenyl-aluminum reagents to cyclic enones. Using commercially available and easily accessible alkenylbromides as alane precursors the present procedure offers a facile access to β-alkenyl-substituted cyclohexanones with high enantioselectivities up to 96%.
Keywords AluminumAlkenesCopperMichael additionAsymmetric catalysis
Identifiers
Full text
Structures
Citation
(ISO format)
MÜLLER, Daniel et al. Creation of Quaternary Stereogenic Centers via Copper-Catalyzed Asymmetric Conjugate Addition of Alkenyl Alanes to α,β-Unsaturated Cyclic Ketones. In: Synlett, 2010, vol. 2010, n° 11, p. 1694 - 1698. https://archive-ouverte.unige.ch/unige:8488

191 hits

9 downloads

Update

Deposited on : 2010-06-29

Export document
Format :
Citation style :