Reduced Expression of SMAD4 Is Associated with Poor Survival in Colon Cancer

Yan, Pu; Klingbiel, Dirk; Saridaki, Zenia; Ceppa, Paola; Curto, Monica; Mckee, Thomas Alexander; Roth, Arnaud; Tejpar, Sabine; Delorenzi, Mauro; Bosman, Fredrik T; Fiocca, Roberto

doi:10.1158/1078-0432.CCR-15-0939

Scientific article

English

Reduced Expression of SMAD4 Is Associated with Poor Survival in Colon Cancer

ContributorsYan, Pu; Klingbiel, Dirk; Saridaki, Zenia; Ceppa, Paola; Curto, Monica; Mckee, Thomas Alexander; Roth, Arnaud; Tejpar, Sabine; Delorenzi, Mauro; Bosman, Fredrik T; Fiocca, Roberto

Published inClinical cancer research, vol. 22, no. 12, p. 3037-3047

Publication date2016

Abstract

SMAD4 loss is associated with the development of metastases and poor prognosis. We evaluated expression of SMAD4 protein and its association with tumor characteristics, including biomarkers and outcome in terms of relapse-free survival and overall survival.

Affiliation entities

Research groups

Lymphomes MALT et réplication virale (807)

Citation (ISO format)

YAN, Pu et al. Reduced Expression of SMAD4 Is Associated with Poor Survival in Colon Cancer. In: Clinical cancer research, 2016, vol. 22, n° 12, p. 3037–3047. doi: 10.1158/1078-0432.CCR-15-0939

Article (Accepted version)

Identifiers

PID : unige:84838
DOI : 10.1158/1078-0432.CCR-15-0939
PMID : 26861460

Journal ISSN1078-0432

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Reduced Expression of SMAD4 Is Associated with Poor Survival in Colon Cancer

SMAD4 loss is associated with the development of metastases and poor prognosis. We evaluated expression of SMAD4 protein and its association with tumor characteristics, including biomarkers and outcome in terms of relapse-free survival and overall survival.

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