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Scientific article
English

Optimization of fast CE analyses of ecstasy derivatives by use of experimental designs

Contributors

Varesio, Emmanuel; Gauvrit, J. -Y.; Longeray, R.; Lantéri, P.; Veuthey, Jean-Luc

Published in

Chromatographia, vol. 50, no. 3-4, p. 195-201

Publication date

1999

Abstract

The separation by capillary electrophoresis of five ecstasy derivatives has been evaluated by means of experimental designs. A full-factorial design and a central composite design were employed to optimize the experimental conditions for a fast separation. With a conventional capillary (62.5 cm length) analytes were separated in less than 8 min. When the capillary length was reduced the analysis time decreased substantially. Comparisons were made between different procedures (e.g. working at a constant field or at constant voltage) and finally, a fast separation of five Ecstasy derivatives was achieved in 1 min.

Keywords

  • Capillary electrophoresis
  • Amphetamines
  • Ecstasy
  • Full-factorial design
  • Central composite design

UNIGE affiliation entities

Citation (ISO format)

VARESIO, Emmanuel et al. Optimization of fast CE analyses of ecstasy derivatives by use of experimental designs. In: Chromatographia, 1999, vol. 50, n° 3-4, p. 195–201. doi: 10.1007/BF02490651

Main files (1)

Article (Published version)

Identifiers

Additional URL for this publication

http://www.springerlink.com/index/10.1007/BF02490651

Journal ISSN

0009-5893
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Technical informations

Creation

28/06/2010 11:27:00

First validation

28/06/2010 11:27:00

Update

26/03/2026 10:47:49

Status update

26/03/2026 10:47:49

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