The rules of sport define a level playing field on which athletes compete. Antidoping policies exist, in theory, to encourage fair play. However, we believe they are unfounded, dangerous, and excessively costly. The need for rules in sports cannot be dismissed. But the anchoring of today's antidoping regulations in the notion of fair play is misguided, since other factors that affect performance—eg, biological and environmental factors—are unchecked. Getting help from one's genes—by being blessed with a performance-enhancing genetic predisposition—is acceptable. Use of drugs is not. Yet both types of advantage are undeserved. Prevailing sports ethics is unconcerned with this contradiction.