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Title

Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles
Authors
Staedler, Davide
Passemard, Solène
Magouroux, Thibaud
Rogov, Andrii
Maguire, Ciaran Manus
Mohamed, Bashir M.
Schwung, Sebastian
Rytz, Daniel
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Published in Nanomedicine. 2015, vol. 11, no. 4, p. 815-824
Abstract Bismuth Ferrite (BFO) nanoparticles (BFO-NP) display interesting optical (nonlinear response) and magnetic properties which make them amenable for bio-oriented diagnostic applications as intra- and extra membrane contrast agents. Due to the relatively recent availability of this material in well dispersed nanometric form, its biocompatibility was not known to date. In this study, we present a thorough assessment of the effects of in vitro exposure of human adenocarcinoma (A549), lung squamous carcinoma (NCI-H520), and acute monocytic leukemia (THP-1) cell lines to uncoated and poly(ethylene glycol)-coated BFO-NP in the form of cytotoxicity, haemolytic response and biocompatibility. Our results support the attractiveness of the functional-BFO towards biomedical applications focused on advanced diagnostic imaging.
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Article (Published version) (1 MB) - document accessible for UNIGE members only Limited access to UNIGE
Other version: http://linkinghub.elsevier.com/retrieve/pii/S1549963415000246
Structures
Faculté des sciences / Section de physique / Groupe de physique appliquée
Research group Groupe Wolf
Citation
(ISO format) 		STAEDLER, Davide et al. Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles. In: Nanomedicine, 2015, vol. 11, n° 4, p. 815-824. https://archive-ouverte.unige.ch/unige:84334

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Deposited on : 2016-06-08

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