Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles

Staedler, Davide; Passemard, Solène; Magouroux, Thibaud; Rogov, Andrii; Maguire, Ciaran Manus; Mohamed, Bashir M.; Schwung, Sebastian; Rytz, Daniel; Jüstel, Thomas; Hwu, Stéphanie; Mugnier, Yannick; Le Dantec, Ronan; Volkov, Yuri; Gerber-Lemaire, Sandrine; Prina-Mello, Adriele; Bonacina, Luigi; Wolf, Jean-Pierre

doi:10.1016/j.nano.2014.12.018

Scientific article

English

Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles

Contributors

Staedler, Davide; Passemard, Solène; Magouroux, Thibaud; Rogov, Andrii; Maguire, Ciaran Manus; Mohamed, Bashir M.; Schwung, Sebastian; Rytz, Daniel; Jüstel, Thomas; Hwu, Stéphanie; Mugnier, Yannick; Le Dantec, Ronan; Volkov, Yuri; Gerber-Lemaire, Sandrine; Prina-Mello, Adriele; Bonacina, Luigi

; Wolf, Jean-Pierre

Published in

Nanomedicine, vol. 11, no. 4, p. 815-824

Publication date

2015

Abstract

Bismuth Ferrite (BFO) nanoparticles (BFO-NP) display interesting optical (nonlinear response) and magnetic properties which make them amenable for bio-oriented diagnostic applications as intra- and extra membrane contrast agents. Due to the relatively recent availability of this material in well dispersed nanometric form, its biocompatibility was not known to date. In this study, we present a thorough assessment of the effects of in vitro exposure of human adenocarcinoma (A549), lung squamous carcinoma (NCI-H520), and acute monocytic leukemia (THP-1) cell lines to uncoated and poly(ethylene glycol)-coated BFO-NP in the form of cytotoxicity, haemolytic response and biocompatibility. Our results support the attractiveness of the functional-BFO towards biomedical applications focused on advanced diagnostic imaging.

UNIGE affiliation entities

Faculté des sciences / Section de physique / Groupe de physique appliquée

UNIGE research groups

Groupe Wolf

Citation (ISO format)

STAEDLER, Davide et al. Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles. In: Nanomedicine, 2015, vol. 11, n° 4, p. 815–824. doi: 10.1016/j.nano.2014.12.018

Article (Published version)

Identifiers

PID : unige:84334
DOI : 10.1016/j.nano.2014.12.018

Additional URL for this publication

http://linkinghub.elsevier.com/retrieve/pii/S1549963415000246

Journal ISSN

1549-9634

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02/06/2016 12:01:00

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31/10/2024 03:37:24

Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles

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Published in

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Abstract

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

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First validation

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Status update

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