Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles

Article Article scientifique Article Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles eng 2015 author Staedler Davide 827614 author Passemard Solène author Magouroux Thibaud 736395 author Rogov Andrii 760651 author Maguire Ciaran Manus author Mohamed Bashir M. author Schwung Sebastian author Rytz Daniel author Jüstel Thomas author Hwu Stéphanie 688984 author Mugnier Yannick 528873 author Le Dantec Ronan 826295 author Volkov Yuri author Gerber-Lemaire Sandrine author Prina-Mello Adriele author Bonacina Luigi 0000-0003-0476-4473 632447 author Wolf Jean-Pierre 0000-0003-3729-958X 631266 815-824 10.1016/j.nano.2014.12.018 1549-9634 http://linkinghub.elsevier.com/retrieve/pii/S1549963415000246 Bismuth Ferrite (BFO) nanoparticles (BFO-NP) display interesting optical (nonlinear response) and magnetic properties which make them amenable for bio-oriented diagnostic applications as intra- and extra membrane contrast agents. Due to the relatively recent availability of this material in well dispersed nanometric form, its biocompatibility was not known to date. In this study, we present a thorough assessment of the effects of in vitro exposure of human adenocarcinoma (A549), lung squamous carcinoma (NCI-H520), and acute monocytic leukemia (THP-1) cell lines to uncoated and poly(ethylene glycol)-coated BFO-NP in the form of cytotoxicity, haemolytic response and biocompatibility. Our results support the attractiveness of the functional-BFO towards biomedical applications focused on advanced diagnostic imaging. Dewey 500.2 35 Groupe de physique appliquée 135 false 676 Groupe Wolf Nanomedicine 11 4 a691fe1a-6e84-409c-a634-c52922217091 Article (Published version) Restricted Staedler2015.pdf 1075073 application/pdf restrictedAccess Faculté des sciences / Section de physique / Groupe de physique appliquée

Title	Published in	Access level	OA Policy	Year	Views	Downloads

Cellular uptake and biocompatibility of bismuth ferrite harmonic advanced nanoparticles	Nanomedicine			2015	673	0

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Hwu, Stéphanie