Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana

Simoes Avello, Claudia; Hostettmann, Kurt; Haouala, Amina; Cuendet, Muriel; Falquet, Jacques; Graz, Bertrand; Christen, Philippe

doi:10.1016/j.ijpddr.2014.07.001

Scientific article

English

Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana

ContributorsSimoes Avello, Claudia; Hostettmann, Kurt; Haouala, Amina; Cuendet, Muriel

; Falquet, Jacques; Graz, Bertrand; Christen, Philippe

Published inInternational Journal for Parasitology, vol. 4, no. 3, p. 338-346

Publication date2014

Abstract

Classical pharmacology has been the basis for the discovery of new chemical entities with therapeutic effects for decades. In natural product research, compounds are generally tested in vivo only after full in vitro characterization. However drug screening using this methodology is expensive, time-consuming and very often inefficient.

Keywords

Reverse pharmacology
Traditional medicine
Anti-malarial phytomedicine
Argemone mexicana

Affiliation entities

Citation (ISO format)

SIMOES AVELLO, Claudia et al. Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana. In: International Journal for Parasitology, 2014, vol. 4, n° 3, p. 338–346. doi: 10.1016/j.ijpddr.2014.07.001

Article (Published version)

Identifiers

PID : unige:83233
DOI : 10.1016/j.ijpddr.2014.07.001

Commercial URLhttp://linkinghub.elsevier.com/retrieve/pii/S2211320714000141

Journal ISSN0020-7519

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Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana

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