Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana

Article Article scientifique Article Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana eng 2014 author Simoes Avello Claudia 630402 author Hostettmann Kurt 135647 author Haouala Amina 604266 author Cuendet Muriel 0000-0002-1523-1907 686755 author Falquet Jacques 22472 author Graz Bertrand 705643 author Christen Philippe 21898 338-346 10.1016/j.ijpddr.2014.07.001 0020-7519 http://linkinghub.elsevier.com/retrieve/pii/S2211320714000141 Classical pharmacology has been the basis for the discovery of new chemical entities with therapeutic effects for decades. In natural product research, compounds are generally tested in vivo only after full in vitro characterization. However drug screening using this methodology is expensive, time-consuming and very often inefficient. Reverse pharmacology Traditional medicine Anti-malarial phytomedicine Argemone mexicana Dewey 580 Dewey 613 Dewey 615 45 Département des sciences végétales 163 31 Section des sciences pharmaceutiques 17 64 Département de santé et médecine communautaires 22A false International Journal for Parasitology 4 3 77c12e1f-ad17-4f41-a5ea-a6c9997855d2 Article (Published version) Public 1-s2.0-S2211320714000141-main.pdf 850450 application/pdf Vignette Public 1-s2.0-S2211320714000141-fx1.jpg 24490 image/jpeg openAccess Faculté des sciences / Section de biologie / Département des sciences végétales Faculté des sciences / Section des sciences pharmaceutiques Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires

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Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana	International Journal for Parasitology			2014	624	349

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Haouala, Amina