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Title

CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis

Authors
Chiappe, Alberto
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Published in European Journal of Clinical Pharmacology. 2006, vol. 62, no. 6, p. 423-429
Collection Open Access - Licence nationale Springer
Abstract To determine whether pharmacogenetic tests such as N-acetyltransferase 2 (NAT2) and cytochrome P450 2E1 (CYP2E1) genotyping are useful in identifying patients prone to antituberculosis drug-induced hepatotoxicity in a cosmopolite population.
Keywords Cosmopolite populationCYP2E1 TaqI polymorphismIsoniazid-induced hepatitisNAT2 genotypeNegative predictive valuePositive predictive value
Identifiers
PMID: 16770646
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Article (Published version) (143 Kb) - public document Free access
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Research group Chimie et protéomique clinique (270)
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VUILLEUMIER, Nicolas et al. CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis. In: European Journal of Clinical Pharmacology, 2006, vol. 62, n° 6, p. 423-429. https://archive-ouverte.unige.ch/unige:83079

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Deposited on : 2016-04-18

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