Cognitive resources can be considered to be key variables in the context of work ability and health, particularly in the aging workforce. However, research on this issue is sparse, lacking a comprehensive examination of specific cognitive functions. Therefore, the aim of the present study was to examine the association of cognitive resources with subjective work ability and health in more detail. In 166 geriatric care workers (mean age 42.1 years, SD = 11.5, range 20–62), subjective work ability and health were assessed. Additionally, a comprehensive battery of cognitive tests measuring crystallized intelligence, cognitive speed, short term memory, working memory, and inhibition was administered in a standardized procedure. Controlling for individual differences in age, education, depressive symptoms, selfregulation strategies (in terms of selective optimization with compensation), and cognitive resources (particularly better performance in short-term memory, working memory, and inhibition) were related to better subjective work ability and health. The present results demonstrate the relation of a variety of specific cognitive functions with subjective work ability and health over and above individual differences in age, education, depressive symptoms, and self-regulation strategies. Implications to explicitly consider a set of cognitive resources in models of work and organizational psychology,particularly with respect to the aging workforce, are discussed.