The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease?

Pagano, Sabrina; Gaertner, Hubert François; Cerini, Fabrice; Mannic, Tiphaine; Satta Poschung, Nathalie; Teixeira, Priscila Camillo; Cutler, Paul; Mach, François; Vuilleumier, Nicolas; Hartley, Oliver

doi:10.1371/journal.pone.0132780

Scientific article

English

The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease?

ContributorsPagano, Sabrina

; Gaertner, Hubert François; Cerini, Fabrice; Mannic, Tiphaine; Satta Poschung, Nathalie; Teixeira, Priscila Camillo; Cutler, Paul; Mach, François; Vuilleumier, Nicolas; Hartley, Oliver

Published inPloS one, vol. 10, no. 7, e0132780

Publication date2015

Abstract

Cardiovascular disease (CVD) is the leading cause of death worldwide and new approaches for both diagnosis and treatment are required. Autoantibodies directed against apolipoprotein A-I (ApoA-I) represent promising biomarkers for use in risk stratification of CVD and may also play a direct role in pathogenesis.

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Citation (ISO format)

PAGANO, Sabrina et al. The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease? In: PloS one, 2015, vol. 10, n° 7, p. e0132780. doi: 10.1371/journal.pone.0132780

Article (Published version)

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Identifiers

PID : unige:81134
DOI : 10.1371/journal.pone.0132780
PMID : 26177543

ISSN of the journal1932-6203

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The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease?

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