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The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease?

ContributorsPagano, Sabrinaorcid; Gaertner, Hubert François; Cerini, Fabrice; Mannic, Tiphaine; Satta Poschung, Nathalie; Teixeira, Priscila Camillo; Cutler, Paul; Mach, François; Vuilleumier, Nicolas; Hartley, Oliverorcid
Published inPloS one, vol. 10, no. 7, e0132780
Publication date2015
Abstract

Cardiovascular disease (CVD) is the leading cause of death worldwide and new approaches for both diagnosis and treatment are required. Autoantibodies directed against apolipoprotein A-I (ApoA-I) represent promising biomarkers for use in risk stratification of CVD and may also play a direct role in pathogenesis.

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PAGANO, Sabrina et al. The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease? In: PloS one, 2015, vol. 10, n° 7, p. e0132780. doi: 10.1371/journal.pone.0132780
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accessLevelPublic CC BY
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Journal ISSN1932-6203
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Creation05/11/2015 10:42:00
First validation05/11/2015 10:42:00
Update time23/01/2025 11:35:00
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