OH
Hartley, Oliver
Affiliation entities
Research groups
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Arylsulfatases and neuraminidases modulate engagement of CCR5 by chemokines by removing key electrostatic interactions | Scientific reports | 2024 | 110 | 47 | |||
Influenza A virus exploits transferrin receptor recycling to enter host cells | Proceedings of the National Academy of Sciences of the United States of America | 2023 | 265 | 137 | |||
Recombinant nanobodies detecting the human cardiac troponin proteins by ELISA | Antibody reports | 2023 | 23 | 26 | |||
C-type lectin receptor agonists elicit functional IL21-expressing Tfh cells and induce primary B cell responses in neonates | Frontiers in immunology | 2023 | 52 | 23 | |||
Precision-engineered peptide and protein analogs: establishing a new discovery platform for potent GPCR modulators | Chimia | 2021 | 187 | 68 | |||
SARS-COV2- infection as a trigger of humoral response against apolipoprotein A-1 | EAS Congress 2021 | 2021 | 270 | 38 | |||
SARS-CoV-2 infection as a trigger of humoral response against apolipoprotein A-1 | European Journal of Clinical Investigation | 2021 | 338 | 221 | |||
Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist | Science advances | 2021 | 206 | 143 | |||
Arrestin recruitment to c-c chemokine receptor 5: potent c-c chemokine ligand 5 analogs reveal differences in dependence on receptor phosphorylation and isoform-specific recruitment bias | Molecular Pharmacology | 2020 | 317 | 139 | |||
RB110 and RB157 antibodies recognize by ELISA specific phosphorylation patterns on CCR5 C-terminal peptides | Antibody Reports | 2020 | 300 | 140 | |||
CCR5 tyrosine sulfation heterogeneity generates cell surface receptor subpopulations with different ligand binding properties | Biochimica et Biophysica Acta - General Subjects | 2020 | 256 | 175 | |||
Prognostic and therapeutic considerations of antibodies against c‐ter apolipoprotein A‐1 in the general population | Clinical & translational immunology | 2020 | 163 | 93 | |||
C-terminus apoa-1 mimetic peptides to detect cognate auto-antibodies and reverse HIV-induced foam cell formation | Atherosclerosis | 2020 | 209 | 0 | |||
Étudier la médecine humaine à l'Université de Genève: Un programme d'études intégré et innovant | Praxis (Bern 1994) | 2020 | 432 | 23 | |||
High-affinity binding of chemokine analogs that display ligand bias at the HIV-1 coreceptor CCR5 | Biophysical Journal | 2019 | 258 | 159 | |||
Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES | Journal of Controlled Release | 2019 | 217 | 544 | |||
Development and pharmacokinetics of a combination vaginal ring for sustained release of dapivirine and the protein microbicide 5P12-RANTES | International Journal of Pharmaceutics | 2019 | 183 | 2 | |||
Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice | Science Translational Medicine | 2019 | 529 | 40 | |||
IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration | JCI Insight | 2019 | 223 | 0 | |||
RB250 and RB251 antibodies recognize the human MitoNEET/CISD1 protein by ELISA | Antibody Reports | 2018 | 461 | 97 | |||
Preventing HIV transmission through blockade of CCR5: rationale, progress and perspectives | Swiss Medical Weekly | 2018 | 584 | 441 | |||
CCR5: Established paradigms and new frontiers for a 'celebrity' chemokine receptor | Cytokine | 2018 | 388 | 9 | |||
Rapid and low-cost multiplex synthesis of chemokine analogs | Journal of Biological Chemistry | 2018 | 383 | 2 | |||
Pharmacokinetics of the Protein Microbicide 5P12-RANTES in Sheep following Single-Dose Vaginal Gel Administration | Antimicrobial Agents and Chemotherapy | 2017 | 404 | 1 | |||
Anti-Apolipoprotein A-1 IgG Predict All-Cause Mortality and Are Associated with Fc Receptor-Like 3 Polymorphisms | Frontiers in Immunology | 2017 | 431 | 198 | |||
Impact of CD14 Polymorphisms on Anti-Apolipoprotein A-1 IgG-Related Coronary Artery Disease Prediction in the General Population | Arteriosclerosis, Thrombosis, and Vascular Biology | 2017 | 428 | 0 | |||
Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1 | Scientific Reports | 2017 | 410 | 201 | |||
Stability of 5P12-RANTES, A Candidate Rectal Microbicide, in Human Rectal Lavage | AIDS Research and Human Retroviruses | 2017 | 371 | 0 | |||
Dual display: phage selection driven by co-engagement of two targets by two different antibody fragments | Protein Engineering, Design and Selection | 2017 | 439 | 1 | |||
Generating Chemokine Analogs with Enhanced Pharmacological Properties Using Phage Display | Methods in enzymology | 2016 | 541 | 5 | |||
Association between anti-apolipoprotein A-1 antibodies and cardiovascular disease in the general population. Results from the CoLaus study | Thrombosis and haemostasis | 2016 | 520 | 7 | |||
Recombinant Antibodies for Academia: A Practical Approach | Chimia | 2016 | 432 | 5 | |||
A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris | Protein expression and purification | 2016 | 524 | 237 | |||
Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants | Molecular therapy | 2016 | 628 | 283 | |||
CCR5 susceptibility to ligand-mediated down-modulation differs between human T lymphocytes and myeloid cells | Journal of leukocyte biology | 2015 | 609 | 12 | |||
Potent Anti-HIV Chemokine Analogs Direct Post-Endocytic Sorting of CCR5 | PloS one | 2015 | 647 | 207 | |||
The Human Autoantibody Response to Apolipoprotein A-I Is Focused on the C-Terminal Helix: A New Rationale for Diagnosis and Treatment of Cardiovascular Disease? | PloS one | 2015 | 522 | 284 | |||
δ-Conotoxins synthesized using an acid-cleavable solubility tag approach reveal key structural determinants for NaV subtype selectivity | The Journal of biological chemistry | 2014 | 636 | 1 | |||
Coordinate-based co-localization-mediated analysis of arrestin clustering upon stimulation of the C-C chemokine receptor 5 with RANTES/CCL5 analogues | Histochemistry and cell biology | 2014 | 582 | 1 | |||
Targeting spare CC chemokine receptor 5 (CCR5) as a principle to inhibit HIV-1 entry | The Journal of biological chemistry | 2014 | 535 | 1 | |||
Definition of human apolipoprotein A-I epitopes recognized by autoantibodies present in patients with cardiovascular diseases | The Journal of biological chemistry | 2014 | 728 | 616 | |||
Autoantibodies to apolipoprotein A-1 as a biomarker of cardiovascular autoimmunity | World journal of cardiology | 2014 | 619 | 222 | |||
Characterization of structure, dynamics, and detergent interactions of the anti-HIV chemokine variant 5P12-RANTES | Biophysical journal | 2013 | 626 | 462 | |||
Antiproton induced DNA damage: proton like in flight, carbon-ion like near rest | Scientific reports | 2013 | 598 | 229 | |||
HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 600 | 288 | |||
Quantitative morphological analysis of arrestin2 clustering upon G protein-coupled receptor stimulation by super-resolution microscopy | Journal of structural biology | 2013 | 641 | 1 | |||
Using glycosaminoglycan/chemokine interactions for the long-term delivery of 5P12-RANTES in HIV prevention | Molecular pharmaceutics | 2013 | 587 | 314 | |||
Identification, structural and pharmacological characterization of τ-CnVA, a conopeptide that selectively interacts with somatostatin sst3 receptor | Biochemical pharmacology | 2013 | 531 | 0 | |||
CCR5 Mutations Distinguish N-Terminal Modifications of RANTES (CCL5) with Agonist versus Antagonist Activity | Journal of virology | 2012 | 589 | 0 | |||
Mechanism and molecular basis for the sodium channel subtype specificity of µ-conopeptide CnIIIC | British journal of pharmacology | 2012 | 580 | 0 | |||
A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors | British journal of pharmacology | 2012 | 651 | 0 | |||
Alteration of synaptic network dynamics by the intellectual disability protein PAK3 | The Journal of neuroscience | 2012 | 672 | 0 | |||
Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots | Nature immunology | 2012 | 611 | 0 | |||
Resistance to the CCR5 inhibitor 5P12-RANTES requires a difficult evolution from CCR5 to CXCR4 coreceptor use | PloS one | 2011 | 692 | 291 | |||
Efficient orthogonal bioconjugation of dendrimers for synthesis of bioactive nanoparticles | Bioconjugate chemistry | 2011 | 615 | 0 | |||
Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5 | Blood | 2011 | 548 | 0 | |||
Deciphering the code for retroviral integration target site selection | PLoS computational biology | 2010 | 654 | 287 | |||
"Resistance" to PSC-RANTES revisited: two mutations in human immunodeficiency virus type 1 HIV-1SF162 or simian-human immunodeficiency virus SHIVSF162-p3 do not confer resistance | Journal of virology | 2010 | 595 | 1 | |||
CC chemokine receptor 5 (CCR5) desensitization: cycling receptors accumulate in the trans-Golgi network | The Journal of biological chemistry | 2010 | 606 | 8 | |||
V-79 Chinese hamster cells irradiated with antiprotons, a study of peripheral damage due to medium and long range components of the annihilation radiation | International journal of radiation biology | 2009 | 585 | 0 | |||
Topically applied recombinant chemokine analogues fully protect macaques from vaginal simian-human immunodeficiency virus challenge | The Journal of infectious diseases | 2009 | 587 | 1 | |||
An engineered CX3CR1 antagonist endowed with anti-inflammatory activity | Journal of leukocyte biology | 2009 | 595 | 1 | |||
Antiproton radiotherapy | Radiotherapy and oncology | 2008 | 557 | 1 | |||
Chemokine analogues show suitable stability for development as microbicides | Journal of acquired immune deficiency syndromes | 2008 | 581 | 2 | |||
Highly potent HIV inhibition: engineering a key anti-HIV structure from PSC-RANTES into MIP-1 beta/CCL4 | Protein engineering, design & selection | 2008 | 625 | 8 | |||
Characterization of new multimeric erythropoietin receptor agonists | Biopolymers | 2008 | 673 | 0 | |||
Engineered CCR5 superagonist chemokine as adjuvant in anti-tumor DNA vaccination | Vaccine | 2008 | 553 | 5 | |||
Targeting chemokine receptors in HIV: a status report | Annual review of pharmacology and toxicology | 2008 | 563 | 0 | |||
Semisynthetic analogues of PSC-RANTES, a potent anti-HIV protein | Bioconjugate chemistry | 2008 | 662 | 5 | |||
Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 560 | 2 | |||
C34, a membrane fusion inhibitor, blocks HIV infection of langerhans cells and viral transmission to T cells | Journal of investigative dermatology | 2007 | 622 | 0 | |||
Analysis of HIV-1-X4 fusion with immature dendritic cells identifies a specific restriction that is independent of CXCR4 levels | Journal of investigative dermatology | 2007 | 573 | 0 | |||
Conserved changes in envelope function during human immunodeficiency virus type 1 coreceptor switching | Journal of virology | 2007 | 463 | 0 | |||
NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation | Biochimie | 2007 | 655 | 0 | |||
Microbicides and other topical strategies to prevent vaginal transmission of HIV | Nature reviews. Immunology | 2006 | 565 | 0 | |||
HIV-1 coreceptor selectivity: structural analogy between HIV-1 V3 regions and chemokine beta-hairpins is not the explanation | Structure | 2006 | 441 | 0 | |||
N-terminal proteolytic processing by cathepsin G converts RANTES/CCL5 and related analogs into a truncated 4-68 variant | Journal of leukocyte biology | 2006 | 550 | 0 | |||
Identification of peptide ligands to the chemokine receptor CCR5 and their maturation by gene shuffling | Molecular immunology | 2006 | 605 | 0 | |||
The biological effectiveness of antiproton irradiation | Radiotherapy and oncology | 2006 | 614 | 0 | |||
Immunogenicity of HIV type 1 gp120 CD4 binding site phage mimotopes | AIDS research and human retroviruses | 2005 | 591 | 0 | |||
Engineering chemokines to develop optimized HIV inhibitors | Current protein and peptide science | 2005 | 513 | 0 | |||
Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases | Journal of neuroimmunology | 2005 | 1,006 | 0 | |||
V3: HIV's switch-hitter | AIDS research and human retroviruses | 2005 | 527 | 0 | |||
Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 665 | 1 | |||
PSC-RANTES blocks R5 human immunodeficiency virus infection of Langerhans cells isolated from individuals with a variety of CCR5 diplotypes | Journal of virology | 2004 | 624 | 0 | |||
COPD results in a reduction in UCP3 long mRNA and UCP3 protein content in types I and IIa skeletal muscle fibers | Journal of cardiopulmonary rehabilitation | 2004 | 639 | 0 | |||
Targeted alpha therapy in vivo: direct evidence for single cancer cell kill using 149Tb-rituximab | European journal of nuclear medicine and molecular imaging | 2004 | 692 | 412 | |||
Synthesis of N alpha-(1-phenyl-2-mercaptoethyl) amino acids, new building blocks for ligation and cyclization at non-cysteine sites: scope and limitations in peptide synthesis | Journal of organic chemistry | 2004 | 547 | 0 | |||
Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5 | Science | 2004 | 608 | 1 | |||
Two mechanisms for human immunodeficiency virus type 1 inhibition by N-terminal modifications of RANTES | Antimicrobial agents and chemotherapy | 2003 | 610 | 2 | |||
Human immunodeficiency virus type 1 entry inhibitors selected on living cells from a library of phage chemokines | Journal of virology | 2003 | 514 | 346 | |||
UCP3 protein regulation in human skeletal muscle fibre types I, IIa and IIx is dependent on exercise intensity | Journal of physiology | 2003 | 558 | 0 | |||
Chemokine-induced cell death in CCR5-expressing neuroblastoma cells | Journal of neuroimmunology | 2003 | 492 | 0 | |||
Synthesis of cyclic peptides from unprotected precursors using removable N alpha-(1-(4-methoxyphenyl)-2-mercaptoethyl) auxiliary | The journal of peptide research | 2003 | 534 | 0 | |||
The use of phage display in the study of receptors and their ligands | Journal of receptor and signal transduction research | 2002 | 566 | 2 | |||
Donor- and ligand-dependent differences in C-C chemokine receptor 5 reexpression | Journal of virology | 2001 | 602 | 1 | |||
Variable sensitivity of CCR5-tropic human immunodeficiency virus type 1 isolates to inhibition by RANTES analogs | Journal of virology | 2000 | 498 | 2 |