en
Scientific article
English

Prevention of stroke recurrence with presumed paradoxical embolism

Published inJournal of neurology, vol. 244, no. 2, p. 71-75
Publication date1997
Abstract

Paradoxical cerebral embolism (PCE) through a patent foramen ovale (PFO) should be considered as a cause of ischemic stroke, particularly in young patients without an alternative cause for stroke. PCE is even more important that it is potentially treatable. However, PCE remains often presumed because it rests upon the rarely demonstrated findings of a deep venous thrombosis and a thrombus lodged in the PFO. Recent studies have shown a rather low stroke recurrence rate in patients with PFO and stroke but suggest that some subgroups of patients with a higher stroke recurrence risk-exist according clinical, echocardiographical and radiological characteristics. For these subgroups, it seems that a more invasive treatment should be required. There are four therapeutic options; antiaggregants, anticoagulation, transcatheter closure of PFO, and surgical closure of PFO. However, these treatments have yet to be evaluated in clinical trials.

Keywords
  • Cerebrovascular Disorders
  • Decision Support Techniques
  • Heart Septal Defects, Atrial
  • Humans
  • Intracranial Embolism and Thrombosis
  • Recurrence
  • Thrombophlebitis
Citation (ISO format)
BOGOUSSLAVSKY, Julien et al. Prevention of stroke recurrence with presumed paradoxical embolism. In: Journal of neurology, 1997, vol. 244, n° 2, p. 71–75. doi: 10.1007/s004150050052
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ISSN of the journal0340-5354
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