Differential cross sections for the production of at least four jets have been measured in proton-proton collisions at √s = 8 TeV at the Large Hadron Collider using the ATLAS detector. Events are selected if the four anti- k t R = 0.4 jets with the largest transverse momentum ( p T ) within the rapidity range | y | < 2.8 are well separated (Δ R 4j min > 0.65), all have p T > 64 GeV, and include at least one jet with p T > 100 GeV. The dataset corresponds to an integrated luminosity of 20.3 fb − 1 . The cross sections, corrected for detector effects, are compared to leading-order and next-to-leading-order calculations as a function of the jet momenta, invariant masses, minimum and maximum opening angles and other kinematic variables.