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Title

Long distance dispersal shaped patterns of human genetic diversity in Eurasia

Authors
Alves, Isabel
Arenas, Miguel
Hanulova, Anna Sramkova
Sousa, Vitor C.
Published in Molecular Biology and Evolution. 2016, vol. 33, no. 4, p. msv332
Abstract Most previous attempts at reconstructing the past history of human populations did not explicitly take geography into account, or considered very simple scenarios of migration and ignored environmental information. However, it is likely that the Last Glacial Maximum (LGM) affected the demography and the range of many species, including our own. Moreover, long-distance dispersal (LDD) may have been an important component of human migrations, allowing fast colonization of new territories and preserving high levels of genetic diversity. Here, we use a high-quality microsatellite dataset genotyped in 22 populations to estimate the posterior probabilities of several scenarios for the settlement of the Old World by modern humans. We considered models ranging from a simple spatial expansion to others including LDD and a LGM-induced range contraction, as well as Neolithic demographic expansions. We find that scenarios with LDD are much better supported by data than models without LDD. Nevertheless, we show evidence that LDD events to empty habitats were strongly prevented during the settlement of Eurasia. This unexpected absence of LDD ahead of the colonization wave front could have been caused by an Allee effect, either due to intrinsic causes such as an inbreeding depression built during the expansion, or to extrinsic causes such as direct competition with archaic humans. Overall, our results suggest only a relatively limited effect of the LGM-contraction on current patterns of human diversity. This is in clear contrast with the major role of LDD migrations, which have potentially contributed to the intermingled genetic structure of Eurasian populations.
Keywords Human evolutionHuman diversityGenetic diversityMigration
Identifiers
Full text
Structures
Research groups TIGERS
Unité d'anthropologie
Envirospace Lab
ISE Pôle Sciences
ISE Pôle Informatique environnementale
ISE Biodiversité
Groupe Sanchez-Mazas
Groupe Currat
Projects FP7: BEAN
FNS: 31003A-156853
Citation
(ISO format)
ALVES, Isabel et al. Long distance dispersal shaped patterns of human genetic diversity in Eurasia. In: Molecular Biology and Evolution, 2016, vol. 33, n° 4, p. msv332. https://archive-ouverte.unige.ch/unige:78266

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Deposited on : 2015-12-07

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