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Title

No neuropathological evidence for a direct topographical relation between microbleeds and cerebral amyloid angiopathy

Authors
Charidimou, Andreas
Published in Acta Neuropathologica Communications. 2015, vol. 3, no. 1, p. 49
Abstract Cerebral microbleeds correspond to blood breakdown products, including hemosiderin-containing macrophages around small vessels on histological examination. Superficial lobar cerebral microbleeds are increasingly recognized on MRI as a biomarker of cerebral amyloid angiopathy but the direct association between amyloid-laden vessels burden and cerebral microbleeds has yet to be validated neuropathologically. To address this issue, we examined the frequency of histopathologically-defined cerebral microbleeds in different brain regions and their relationship with cerebral amyloid angiopathy in a large autopsy population.
Identifiers
PMID: 26268348
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Research groups Groupe Giannakopoulos Panteleimon (psychiatrie générale) (201)
Démence du sujet âgé, troubles cognitifs, la symptomatologie cognitive (577)
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KOVARI, Eniko Veronika et al. No neuropathological evidence for a direct topographical relation between microbleeds and cerebral amyloid angiopathy. In: Acta Neuropathologica Communications, 2015, vol. 3, n° 1, p. 49. https://archive-ouverte.unige.ch/unige:77160

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Deposited on : 2015-11-11

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