UNIGE document Scientific Article
previous document  unige:7698  next document
add to browser collection
Title

Proviral HIV-DNA predicts viral rebound and viral setpoint after structured treatment interruptions

Authors
Gunthard, Huldrych
Fagard, Catherine
Joos, Beda
Perneger, T. V.
Published in AIDS. 2004, vol. 18, no. 14, p. 1951-1953
Abstract In HIV-1-infected patients with long-term undetectable viraemia on highly active antiretroviral treatment (HAART), we found that pre-HAART plasma viraemia and the baseline proviral DNA level were significantly associated with the viraemia setpoint during scheduled treatment interruptions. In long-term treated patients, pre-HAART viraemia may not be available, and in these circumstances proviral DNA, measured at the time of scheduled treatment interruption, can help to identify patients likely to reach a low viraemia setpoint after treatment interruption.
Keywords Antiretroviral Therapy, Highly ActiveCohort StudiesDNA, ViralHIV Infections/drug therapy/ genetics/virologyHIV-1/ geneticsHumansMultivariate AnalysisMutation/geneticsRNA, Viral/geneticsViremia/genetics/virology
Identifiers
PMID: 15353981
Full text
Structures
Citation
(ISO format)
YERLY FERRILLO, Sabine et al. Proviral HIV-DNA predicts viral rebound and viral setpoint after structured treatment interruptions. In: AIDS, 2004, vol. 18, n° 14, p. 1951-1953. https://archive-ouverte.unige.ch/unige:7698

178 hits

0 download

Update

Deposited on : 2010-06-21

Export document
Format :
Citation style :