Exploiting the phase of NMR signals to carry useful information. Application to the measurement of chemical shifts in aliased 2D spectra

Ramirez Gualito, Karla Elizabeth; Jeannerat, Damien

doi:10.1002/mrc.4301

Scientific article

English

Exploiting the phase of NMR signals to carry useful information. Application to the measurement of chemical shifts in aliased 2D spectra

Contributors

Ramirez Gualito, Karla Elizabeth; Jeannerat, Damien

Published in

Magnetic resonance in chemistry, vol. 53, no. 11, p. 901-907

Publication date

2015

Abstract

Taking advantage of the phase of nuclear magnetic resonance (NMR) signals to encode NMR information is not easy because of their low precision and their sensitivity to nearby signals. We nevertheless demonstrated that the phase in indirect dimension of 1H–13C heteronuclear single quantum coherence (HSQC) signals could provide carbon chemical shifts at low, but sufficient precision to resolve the ambiguities of the chemical shifts in aliased spectra. This approach, we called phase-encoding of the aliasing order Na (PHANA), only requires inserting a constant delay during the t1 evolution time to obtain spectra where signals with mixed phases can be decoded at the processing to reconstruct full spectra with a 15-fold increase in resolution

Keywords

NMR
13C
1H
HSQC
Fast method
Spectral aliasing
Phase coding of chemical shifts
PHANA
Cyclosporine A

Note

https://arxiv.org/submit/1914274

UNIGE affiliation entities

Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

UNIGE research groups

Groupe Jeannerat

Citation (ISO format)

RAMIREZ GUALITO, Karla Elizabeth, JEANNERAT, Damien. Exploiting the phase of NMR signals to carry useful information. Application to the measurement of chemical shifts in aliased 2D spectra. In: Magnetic resonance in chemistry, 2015, vol. 53, n° 11, p. 901–907. doi: 10.1002/mrc.4301

Article (Published version)

Identifiers

PID : unige:76511
DOI : 10.1002/mrc.4301
arXiv : 1914274

Journal ISSN

0749-1581

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Exploiting the phase of NMR signals to carry useful information. Application to the measurement of chemical shifts in aliased 2D spectra

Contributors

Published in

Publication date

Abstract

Keywords

Note

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

Main files (1)

Identifiers

Journal ISSN

Technical informations

Creation

First validation

Update

Status update

Last indexation