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Clinical features of acute retroviral syndrome differ by route of infection but not by gender and age

Vanhems, Philippe
Routy, J. P.
Baratin, Dominique
Maenza, Janine
Carr, Andrew
Trepo, Christian
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Published in Journal of Acquired Immune Deficiency Syndromes. 2002, vol. 31, no. 3, p. 318-321
Abstract The rate of HIV disease progression is associated with the severity of the acute retroviral syndrome (ARS). We explored the clinical features of ARS by gender, age and route of infection among 378 individuals with documented ARS enrolled in 5 prospective cohort studies with similar enrollment criteria. No major differences were detected by gender or by age. Several symptoms were reported less frequently in the injecting drug users as compared with infection acquired through sexual contacts (either heterosexual or homosexual). This was observed in particular for fever (50% vs. 77%, p=.001), skin rash (21% vs. 51%, p=.001), pharyngitis (18% vs. 43%, p=.004), and myalgia (29% vs. 52%, p=.01). Genital ulcerations were present only in cases of sexual exposure to HIV. Injecting drug users had or reported symptoms associated with the ARS less frequently than persons acquiring HIV via sexual transmission.
Keywords Acute DiseaseAdolescentAdultAge FactorsFemaleHIV Infections/diagnosis/ etiology/transmissionHumansMaleSex FactorsSexual BehaviorSubstance Abuse, Intravenous/complicationsSyndrome
PMID: 12439207
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VANHEMS, Philippe et al. Clinical features of acute retroviral syndrome differ by route of infection but not by gender and age. In: Journal of Acquired Immune Deficiency Syndromes, 2002, vol. 31, n° 3, p. 318-321. doi: 10.1097/00019048-200208000-00034 https://archive-ouverte.unige.ch/unige:7641

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Deposited on : 2010-06-21

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