Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion

Mezey, E; Kiss, Jozsef Zoltan

doi:10.1073/pnas.82.1.245

Scientific article

Open access

English

Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion

ContributorsMezey, E; Kiss, Jozsef Zoltan

Published inProceedings of the National Academy of Sciences of the United States of America, vol. 82, no. 1, p. 245-247

Publication date1985

Abstract

Vasoactive intestinal polypeptide (VIP) immunoreactivity is present in varicosities and fibers in the hypothalamic paraventricular nucleus (PVN) in normal control animals. Adrenalectomy and lactation combined with colchicine treatment results in the appearance of a large population of VIP-immunopositive cell bodies in the parvocellular part of the PVN. Adrenalectomy, as well as lactation, significantly increases the number of VIP-positive fibers in the external zone of the median eminence. These observations suggest that the VIP-immunopositive neurons in the PVN may participate in regulating prolactin and corticotropin secretion.

Keywords

Adrenalectomy
Animals
Colchicine/pharmacology
Female
Immunologic Techniques
Lactation
Male
Paraventricular Hypothalamic Nucleus/cytology/physiology
Pregnancy
Prolactin/secretion
Rats
Rats, Inbred Strains
Vasoactive Intestinal Peptide/physiology

Affiliation

Faculté de médecine / Section de médecine fondamentale / Département de neurosciences fondamentales

Research group

Progéniteurs neuronaux (141)

Citation (ISO format)

MEZEY, E, KISS, Jozsef Zoltan. Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion. In: Proceedings of the National Academy of Sciences of the United States of America, 1985, vol. 82, n° 1, p. 245–247. doi: 10.1073/pnas.82.1.245

Article (Published version)

Identifiers

PID : unige:74765
DOI : 10.1073/pnas.82.1.245
PMID : 3881755

ISSN of the journal0027-8424

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Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion

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