Scientific article
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English

Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion

Publication date

1985

Abstract

Vasoactive intestinal polypeptide (VIP) immunoreactivity is present in varicosities and fibers in the hypothalamic paraventricular nucleus (PVN) in normal control animals. Adrenalectomy and lactation combined with colchicine treatment results in the appearance of a large population of VIP-immunopositive cell bodies in the parvocellular part of the PVN. Adrenalectomy, as well as lactation, significantly increases the number of VIP-positive fibers in the external zone of the median eminence. These observations suggest that the VIP-immunopositive neurons in the PVN may participate in regulating prolactin and corticotropin secretion.

Keywords

  • Adrenalectomy
  • Animals
  • Colchicine/pharmacology
  • Female
  • Immunologic Techniques
  • Lactation
  • Male
  • Paraventricular Hypothalamic Nucleus/cytology/physiology
  • Pregnancy
  • Prolactin/secretion
  • Rats
  • Rats, Inbred Strains
  • Vasoactive Intestinal Peptide/physiology

UNIGE research groups

Citation (ISO format)

MEZEY, E, KISS, Jozsef Zoltan. Vasoactive intestinal peptide-containing neurons in the paraventricular nucleus may participate in regulating prolactin secretion. In: Proceedings of the National Academy of Sciences of the United States of America, 1985, vol. 82, n° 1, p. 245–247. doi: 10.1073/pnas.82.1.245

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Article (Published version)

Identifiers

Journal ISSN

0027-8424
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215downloads

Technical informations

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31/07/2015 15:45:00

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31/07/2015 15:45:00

Update

14/03/2023 23:34:17

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