Scientific article
Open access

The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000

Published inNucleic acids research, vol. 28, no. 1, p. 45-48
Publication date2000

SWISS-PROT is a curated protein sequence database which strives to provide a high level of annotation (such as the description of the function of a protein, its domains structure, post-translational modifications, variants, etc.), a minimal level of redundancy and high level of integration with other databases. Recent developments of the database include format and content enhancements, cross-references to additional databases, new documentation files and improvements to TrEMBL, a computer-annotated supplement to SWISS-PROT. TrEMBL consists of entries in SWISS-PROT-like format derived from the translation of all coding sequences (CDSs) in the EMBL Nucleotide Sequence Database, except the CDSs already included in SWISS-PROT. We also describe the Human Proteomics Initiative (HPI), a major project to annotate all known human sequences according to the quality standards of SWISS-PROT. SWISS-PROT is available at: http://www.expasy.ch/sprot/ and http://www.ebi.ac.uk/swissprot/

  • Animals
  • Databases, Factual
  • Genome
  • Humans
  • Proteins/chemistry/genetics/metabolism
  • Systems Integration
Research group
Citation (ISO format)
BAIROCH, Amos Marc, APWEILER, Rolf. The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000. In: Nucleic acids research, 2000, vol. 28, n° 1, p. 45–48. doi: 10.1093/nar/28.1.45
Main files (1)
Article (Published version)
ISSN of the journal0305-1048

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